In cancerous cells, significant changes occur in the activity of signaling pathways affecting a
wide range of cellular activities ranging from growth and proliferation to apoptosis …

DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …

As a quinonemethide triterpenoid extracted from species of the Celastraceae and
Hippocrateaceae, pristimerin has been shown potent anti-cancer effects. Specifically, it was …

A reversible post-translational protein modification which involves addition of N-
acetylglucosamine (GlcNAc) onto hydroxyl groups of serine and/or threonine residues which …

Reducing backfat thickness (BFT), determined by subcutaneous fat deposition, is vital in
Chinese developed pig breeds. The level of miR-503 in the backfat of Guanzhong Black …

Cellular systems have evolved numerous mechanisms to adapt to environmental stimuli,
underpinned by dynamic patterns of gene expression. In addition to gene transcription …

Abstract Golgi Membrane Protein 1 (GOLM1) has been identified as a prime target for
cancer therapy because it overexpresses in many solid tumors, increases tumor growth and …

Prostate cancer (PCa) morbidity in the majority of patients is due to metastatic events, which
are a clinical obstacle. Therefore, a better understanding of the mechanism underlying …

Purpose Although surgical resection combined with neoadjuvant radiation therapy can
reduce the local recurrence rate of rectal cancer, not all patients benefit from neoadjuvant …

Background: Gastric cancer is the most common gastrointestinal cancer worldwide. The
latest data showed that it was the fourth leading cause of cancer-related death. The …