Prevention and treatment of cancers by immune modulating nutrients

NB Janakiram, A Mohammed, V Madka… - Molecular nutrition & …, 2016 - Wiley Online Library
Epidemiological and laboratory data support the protective effects of bioactive nutrients in
our diets for various diseases. Along with various factors, such as genetic history, alcohol …

PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells

H Luo, Y Yang, J Duan, P Wu, Q Jiang, C Xu - Cell death & disease, 2013 - nature.com
Mounting evidence shows that selenium possesses chemotherapeutic potential against
tumor cells, including leukemia, prostate cancer and colorectal cancer (CRC) cells …

Synthesis and antiproliferative activity of novel selenoester derivatives

E Domínguez-Álvarez, D Plano, M Font, A Calvo… - European journal of …, 2014 - Elsevier
A series of 31 new selenoesters were synthesized and their cytotoxic activity was evaluated
against a prostate cancer cell line (PC-3). The most active compounds were also tested …

[PDF][PDF] The effect of nutritional elements on the immune system

K Karacabey, N Ozdemir - J Obes Wt Loss Ther, 2012 - academia.edu
Journal of Obesity & Weight Loss Therapy Page 1 Journal of Obesity & Weight Loss Therapy
deals with the clinical study of obesity, dietary changes and body mass highlight. Obesity and …

[PDF][PDF] Sodium selenite induces apoptosis in colon cancer cells via Bax-dependent mitochondrial pathway

Z Li, J Meng, TJ Xu, XY Qin… - Eur Rev Med Pharmacol …, 2013 - europeanreview.org
OBJECTIVES: We aimed to eluci-date a possible mechanism of action by investigating the
effects of selenium (Se) on cell cycle arrest and apoptosis in colorectal cancer cells …

Synthesis of novel organic selenium compounds and speciation of their metabolites in biofortified kale sprouts

P Zagrodzki, P Paśko, E Domínguez-Álvarez… - Microchemical …, 2022 - Elsevier
Sprouts enriched with selenium offer increased nutritional value and chemopreventive
properties raising interest in their contribution to the human diet. The effect of selenium …

The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells

P Wu, KJ Shi, JJ An, YL Ci, F Li, KY Hui, Y Yang… - Cell death & …, 2014 - nature.com
Inhibitor-of-apoptosis protein (IAP) inhibitors have been reported to synergistically reduce
cell viability in combination with a variety of chemotherapeutic drugs via targeted cellular IAP …

[HTML][HTML] Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells

J Zhao, R Zhou, K Hui, Y Yang, QY Zhang, Y Ci, L Shi… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Glutaminolysis is important for metabolism and biosynthesis of cancer cells, and GLS is
essential in the process. Selenite is widely regarded as a chemopreventive agent against …

Chronic sodium selenate treatment restores deficits in cognition and synaptic plasticity in a murine model of tauopathy

T Ahmed, A Van der Jeugd, R Caillierez… - Frontiers in Molecular …, 2020 - frontiersin.org
A major goal in diseases is identifying a potential therapeutic agent that is cost-effective and
can remedy some, if not all, disease symptoms. In Alzheimer's disease (AD), aggregation of …

Selenite induces apoptosis in colorectal cancer cells via AKT-mediated inhibition of β-catenin survival axis

H Luo, Y Yang, F Huang, F Li, Q Jiang, K Shi, C Xu - Cancer letters, 2012 - Elsevier
Mounting evidence reveals that selenium possesses chemotherapeutic potential against
cancer cells. However, the molecular mechanisms underlying the anti-cancer effect of …