An updated review on marine anticancer compounds: The use of virtual screening for the discovery of small-molecule cancer drugs
Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …
structural diversity and have shown a variety of biological activities. These compounds are …
Mechanobiology of tumor growth
Over the past decade, researchers have highlighted the importance of mechanical cues of
the metastatic niche such as matrix stiffness, topography, mechanical stresses, and …
the metastatic niche such as matrix stiffness, topography, mechanical stresses, and …
Expansion of patient-derived circulating tumor cells from liquid biopsies using a CTC microfluidic culture device
The development of personalized cancer therapy depends on a robust system to monitor the
patient's individual response to anticancer treatment. Anticancer drug efficacy has been …
patient's individual response to anticancer treatment. Anticancer drug efficacy has been …
Recent advances in single-cell analysis by mass spectrometry
L Yin, Z Zhang, Y Liu, Y Gao, J Gu - Analyst, 2019 - pubs.rsc.org
Cells are the most basic structural units that play vital roles in the functioning of living
organisms. Analysis of the chemical composition and content of a single cell plays a vital …
organisms. Analysis of the chemical composition and content of a single cell plays a vital …
Single-cell analysis of circulating tumour cells: enabling technologies and clinical applications
Multimodal analysis of circulating tumour cells (CTCs) has the potential to provide
remarkable insight for cancer development and metastasis. CTCs and CTC clusters …
remarkable insight for cancer development and metastasis. CTCs and CTC clusters …
Coral and coral-associated microorganisms: A prolific source of potential bioactive natural products
Marine invertebrates and their associated microorganisms are rich sources of bioactive
compounds. Among them, coral and its associated microorganisms are promising providers …
compounds. Among them, coral and its associated microorganisms are promising providers …
High throughput screening of complex biological samples with mass spectrometry–from bulk measurements to single cell analysis
High throughput screening (HTS) of molecular analytes is in high demand from and
implemented in many areas of chemistry, medicine and industrial biotechnology including …
implemented in many areas of chemistry, medicine and industrial biotechnology including …
Tumorigenesis as a process of gradual loss of original cell identity and gain of properties of neural precursor/progenitor cells
Y Cao - Cell & Bioscience, 2017 - Springer
Cancer is a complex disease without a unified explanation for its cause so far. Our recent
work demonstrates that cancer cells share similar regulatory networks and characteristics …
work demonstrates that cancer cells share similar regulatory networks and characteristics …
Pirfenidone reduces immune-suppressive capacity of cancer-associated fibroblasts through targeting CCL17 and TNF-beta
Various factors in the tumor microenvironment (TME) regulate the expression of PD-L1 in
carcinoma cells. The cancer-associated fibroblasts (CAFs) play a crucial role in regulating …
carcinoma cells. The cancer-associated fibroblasts (CAFs) play a crucial role in regulating …
Developmental origins and oncogenic pathways in malignant brain tumors
QR Lu, L Qian, X Zhou - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Brain tumors such as adult glioblastomas and pediatric high‐grade gliomas or
medulloblastomas are among the leading causes of cancer‐related deaths, exhibiting poor …
medulloblastomas are among the leading causes of cancer‐related deaths, exhibiting poor …