New tools for higher-resolution fetal genome analysis including microarray and next-
generation sequencing have revolutionized prenatal screening. This article provides …

Single-cell analysis is a rapidly evolving to characterize molecular information at the
individual cell level. Here, we present a new approach with the potential to overcome …

The tumor microenvironment (TME) comprises a heterogeneous number and type of cellular
and noncellular components that vary in the context of molecular, genomic and epigenomic …

The use of salvaged blood in oncological surgery has been a matter of controversy over the
years. This is due to the concern of systemic dissemination of reinfused tumour cells. Recent …

A signal amplification protocol based on mass spectrometry (MS) was developed to profile
simultaneously multiple biomarkers from a single cell using various mass label (ML) …

In the present work we show that multiple lung cancer cell lines contain cisplatin resistant
cell subpopulations expressing the Colony-Stimulating-Factor-Receptor-1 (CSF-1R) and …

Tumor heterogeneity is an important feature of colorectal cancer (CRC) manifested by
dynamic changes in gene expression, protein expression, and availability of different tumor …

Cellular functions emerge from the collective action of a large number of different proteins.
Understanding how these protein networks operate requires monitoring their components in …

Cancer heterogeneity is a significant factor in response to treatment and escape leading to
relapse. Within an individual cancer, especially blood cancers, there exists multiple …

In the past few decades, the studies of extrachromosomal DNA (ecDNA), which existed
independently of chromosomes, were tepid. However, recent studies on ecDNA rekindled …