Microdevices for non-invasive detection of bladder cancer

C Tzouanas, JSY Lim, Y Wen, JP Thiery, BL Khoo - Chemosensors, 2017 - mdpi.com
Bladder cancer holds the record for the highest lifetime cost on a per-patient basis. This is
due to high recurrence rates, which necessitate invasive and costly long-term evaluation …

Application and prospects of single cell sequencing in tumors

RH Huang, LX Wang, J He, W Gao - Biomarker Research, 2021 - Springer
Cancer is an intricate disease with inherent intra-tumor heterogeneity at the cellular level
because of genetic changes and environmental differences. Cellular heterogeneity exists …

Moonshot objectives: catalyze new scientific breakthroughs—proteogenomics

KD Rodland, P Piehowski, RD Smith - The Cancer Journal, 2018 - journals.lww.com
Breaking down the silos between disciplines to accelerate the pace of cancer research is a
key paradigm for the Cancer Moonshot. Molecular analyses of cancer biology have tended …

Quantitative single-cell analysis of isolated cancer cells with a microwell array

H Kim, S Park, BJ Kang, Y Jeong, H Lee… - ACS Combinatorial …, 2018 - ACS Publications
The heterogeneous nature of tumor-cell populations suggests that quantitative analysis at
the single-cell level may provide better insights into cancer biology. Specifically, detection of …

Dielectrophoresis-Assisted Self-Digitization Chip for High-Efficiency Single-Cell Analysis

Y Qin, L Wu, DT Chiu - Single-Cell Assays: Microfluidics, Genomics, and …, 2023 - Springer
Single-cell analysis of cell phenotypic information such as surface protein expression and
nucleic acid content is essential for understanding heterogeneity within cell populations …

Protein–Protein Interactions in Cancer

KM Poluri, K Gulati, DK Tripathi, N Nagar - Protein-Protein Interactions …, 2023 - Springer
Cancerous state is often associated with the aberrant expression of several critical proteins,
which in turn, modulate interactions with other proteins. Therefore, researchers have tried to …

[HTML][HTML] Simulation and fabrication of an integrating well-aligned silicon nanowires substrate for trapping circulating tumor cells labeled with Fe3O4 nanoparticles in a …

V Ghafouri, M Badieirostami, M Fathipour - BioImpacts: BI, 2022 - ncbi.nlm.nih.gov
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Introduction: Circulating tumor cells (CTCs) are the transformed tumor cells that can …

A Low-cost Microfluidic Approach for Single Cell Analysis of Rare Cells

P Radfar - 2023 - opus.lib.uts.edu.au
Traditional biopsy methods, while detailed, are often invasive, causing discomfort and not
always feasible for deep-seated tissues. Liquid biopsy, detecting rare cells in body fluids …

Stromal barriers within the tumor microenvironment and obstacles to nanomedicine

HY Tanaka, MR Kano - Cancer Drug Delivery Systems Based on the …, 2019 - Springer
Nanomedicine has been heralded as the elusive “magic bullet” of cancer
chemotherapeutics ever since the description of the Enhanced Permeability and Retention …

Structural and functional intratumor heterogeneities in glioblastoma: a spacetime odyssey at single-cell level

A Idbaih - Annals of Oncology, 2017 - annalsofoncology.org
Glioblastoma (GBM) is the most prevalent primary brain cancer and one of the most
challenging cancers to treat in adults. Indeed, the prognosis for patients with GBM remains …