Adaptive optics (AO) is a technique that corrects for optical aberrations. It was originally
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …

In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …

The last decade has seen the development of a wide set of tools, such as wavefront
shaping, computational or fundamental methods, that allow us to understand and control …

Retrieving the pupil phase of a beam path is a central problem for optical systems across
scales, from telescopes, where the phase information allows for aberration correction, to the …

Optical imaging has had a central role in elucidating the underlying biological and
physiological mechanisms in living specimens owing to its high spatial resolution, molecular …

Imaging through scattering is an important yet challenging problem. Tremendous progress
has been made by exploiting the deterministic input–output “transmission matrix” for a fixed …

Long-term subcellular intravital imaging in mammals is vital to study diverse intercellular
behaviors and organelle functions during native physiological processes. However, optical …

Light-based in-vivo brain imaging relies on light transport over large distances of highly
scattering tissues. Scattering gradually reduces imaging contrast and resolution, making it …

Pushing the frontier of fluorescence microscopy requires the design of enhanced
fluorophores with finely tuned properties. We recently discovered that incorporation of four …

Optical techniques offer a wide variety of applications as light-matter interactions provide
extremely sensitive mechanisms to probe or treat target media. Most of these …