Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
Exosome: a review of its classification, isolation techniques, storage, diagnostic and targeted therapy applications
Y Zhang, J Bi, J Huang, Y Tang, S Du… - International journal of …, 2020 - Taylor & Francis
Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic
acids, proteins, lipids and other bioactive substances to play a role in the body's …
acids, proteins, lipids and other bioactive substances to play a role in the body's …
[HTML][HTML] Release mechanisms of major DAMPs
Damage-associated molecular patterns (DAMPs) are endogenous molecules which foment
inflammation and are associated with disorders in sepsis and cancer. Thus, therapeutically …
inflammation and are associated with disorders in sepsis and cancer. Thus, therapeutically …
[HTML][HTML] The role of exosomes and their applications in cancer
Y Zhou, Y Zhang, H Gong, S Luo, Y Cui - International journal of …, 2021 - mdpi.com
Exosomes are very small extracellular vesicles secreted by multiple cell types and are
extensively distributed in various biological fluids. Recent research indicated that exosomes …
extensively distributed in various biological fluids. Recent research indicated that exosomes …
Tumor-derived extracellular vesicles: The metastatic organotropism drivers
The continuous growing, spreading, and metastasis of tumor cells depend on intercellular
communication within cells resident in a tissue environment. Such communication is …
communication within cells resident in a tissue environment. Such communication is …
Application of extracellular vesicles derived from mesenchymal stem cells as potential therapeutic tools in autoimmune and rheumatic diseases
Mesenchymal stem cells (MSCs) have been proven to have superior potential to be used as
therapeutic candidates in various disorders. Nevertheless, the clinical application of these …
therapeutic candidates in various disorders. Nevertheless, the clinical application of these …
Microfluidic‐based exosome analysis for liquid biopsy
B Lin, Y Lei, J Wang, L Zhu, Y Wu, H Zhang… - Small …, 2021 - Wiley Online Library
Liquid biopsy offers non‐invasive and real‐time molecular profiling of individual patients,
and is thus considered a revolutionary technology in precision medicine. Exosomes have …
and is thus considered a revolutionary technology in precision medicine. Exosomes have …
Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy
Three major approaches of cancer therapy can be enunciated as delivery of biotherapeutics,
tumor image analysis, and immunotherapy. Liposomes, artificial fat bubbles, are long known …
tumor image analysis, and immunotherapy. Liposomes, artificial fat bubbles, are long known …
[HTML][HTML] Targeted inhibition of tumor-derived exosomes as a novel therapeutic option for cancer
Y Li, ZK Chen, X Duan, HJ Zhang, BL Xiao… - … & molecular medicine, 2022 - nature.com
Mounting evidence indicates that tumor-derived exosomes (TDEs) play critical roles in tumor
development and progression by regulating components in the tumor microenvironment …
development and progression by regulating components in the tumor microenvironment …