Controlled drug delivery systems: current status and future directions

S Adepu, S Ramakrishna - Molecules, 2021 - mdpi.com
The drug delivery system enables the release of the active pharmaceutical ingredient to
achieve a desired therapeutic response. Conventional drug delivery systems (tablets …

Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

Lipid nanoparticles for drug delivery

L Xu, X Wang, Y Liu, G Yang… - Advanced …, 2022 - Wiley Online Library
Lipid nanoparticles have attracted significant interests in the last two decades, and have
achieved tremendous clinical success since the first clinical approval of Doxil in 1995. At the …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles

ML Formica, DA Real, ML Picchio, E Catlin… - Applied Materials …, 2022 - Elsevier
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Nanomaterials in tumor immunotherapy: new strategies and challenges

X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

Lipid nanoparticles as carriers for bioactive delivery

N Dhiman, R Awasthi, B Sharma, H Kharkwal… - Frontiers in …, 2021 - frontiersin.org
Nanotechnology has made a great impact on the pharmaceutical, biotechnology, food, and
cosmetics industries. More than 40% of the approved drugs are lipophilic and have poor …

[HTML][HTML] Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of in vivo imaging

HN Jung, SY Lee, S Lee, H Youn, HJ Im - Theranostics, 2022 - ncbi.nlm.nih.gov
Lipid nanoparticles (LNPs) have been one of the most successful nano-delivery vehicles
that enable efficient delivery of cytotoxic chemotherapy agents, antibiotics, and nucleic acid …

Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Lipid-based nanoparticles for drug/gene delivery: An overview of the production techniques and difficulties encountered in their industrial development

M Mehta, TA Bui, X Yang, Y Aksoy, EM Goldys… - ACS Materials …, 2023 - ACS Publications
Over the past decade, the therapeutic potential of nanomaterials as novel drug delivery
systems complementing conventional pharmacology has been widely acknowledged …