Atractylenolide I Alleviates Indomethacin-Induced Gastric Ulcers in Rats by Inhibiting NLRP3 Inflammasome Activation

C Yuan, C Yu, Q Sun, M Xiong, B Ren… - Journal of Agricultural …, 2024 - ACS Publications
Atractylodes macrocephala Koidz, a traditional Chinese medicine, contains atractylenolide I
(ATR-I), which has potential anticancer, anti-inflammatory, and immune-modulating …

WeiNaiAn capsule attenuates intestinal mucosal injury and regulates gut microbiome in indomethacin-induced rat

Y Zheng, J Song, L Huang, G Chen, N Ning… - … International Journal of …, 2024 - Elsevier
Indomethacin, as a non-steroidal anti-inflammatory drugs, is widely used in the clinic.
However, it can cause severe injury to the gastrointestinal tract and the incidence is …

Melatonin activates Nrf2/HO‐1 signalling pathway to antagonizes oxidative stress‐induced injury via melatonin receptor 1 (MT1) in cryopreserved mice ovarian tissue

CY Wei, X Zhang, LN Si, WH Shu… - … in Domestic Animals, 2024 - Wiley Online Library
Our previous research has shown that melatonin (MLT) can reduce cryopreserved ovarian
damage in mice. Yet, the molecular mechanism of MLT protection is still unclear. Some …

Integrated ultra‐high‐performance liquid chromatography coupled with quadrupole‐orbitrap mass spectrometry‐based components analysis and network …

R Wang, S Tang, L Huang, Z Chen, Y Li… - Journal of …, 2024 - Wiley Online Library
Gancao Xiexin Decoction (GCXXD) is a traditional Chinese decoction that is often used in
treating gastric ulcers. However, the substance basis and mechanism of action remain …

Curcumin regulates inflammation and apoptosis through PARP-1 and NF-κB in ethanol-induced gastric ulcer model

M Keçeci, MA Ferah, H Khoshvaghti… - Indian Journal of …, 2024 - or.niscpr.res.in
Curcumin is a natural polyphenol with antioxidant, antiapoptotic and anti-inflammatory
properties. In the present study, we explored the roles of PARP-1 and NF-κB molecules in …