Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications

C Englert, JC Brendel, TC Majdanski, T Yildirim… - Progress in Polymer …, 2018 - Elsevier
The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …

The role of nanotechnology in combating biofilm-based antibiotic resistance

B Malaekeh-Nikouei, BSF Bazzaz, E Mirhadi… - Journal of Drug Delivery …, 2020 - Elsevier
Many serious infections result from persistent microbial biofilms that do not respond to
conventional antibiotic therapy. Various therapeutic approaches have been developed and …

[HTML][HTML] Material considerations for fused-filament fabrication of solid dosage forms

E Fuenmayor, M Forde, AV Healy, DM Devine… - Pharmaceutics, 2018 - mdpi.com
Material choice is a fundamental consideration when it comes to designing a solid dosage
form. The matrix material will ultimately determine the rate of drug release since the physical …

Oral controlled and sustained drug delivery systems: Concepts, advances, preclinical, and clinical status

G Kaur, J Grewal, K Jyoti, UK Jain, R Chandra… - Drug targeting and …, 2018 - Elsevier
Owing to the difficulty in developing new drug moieties, greater emphasis is being given to
developing new drug delivery systems for existing drugs. The oral route is the major …

Amorphous solid dispersions: Utilization and challenges in preclinical drug development within AstraZeneca

AB Anane-Adjei, E Jacobs, SC Nash, S Askin… - International Journal of …, 2022 - Elsevier
The poor aqueous solubility of many active pharmaceutical ingredients (APIs) dominates
much of the early drug development portfolio and poses a major challenge in …

Drug–gut microbiota interactions: implications for neuropharmacology

J Walsh, BT Griffin, G Clarke… - British journal of …, 2018 - Wiley Online Library
The fate and activity of drugs are frequently dictated not only by the host per se but also by
the microorganisms present in the gastrointestinal tract. The gut microbiome is known to …

Magnetic nanocrystalline cellulose: Azithromycin adsorption and in vitro biological activity against melanoma cells

T da Rosa Salles, F da Silva Bruckamann… - Journal of Polymers and …, 2022 - Springer
This study reports a simple methodology of obtaining magnetic nanocrystalline cellulose
under very mild conditions employing only Fe2+ as the iron source, enabling the control of …

Effect of lignin on the release rate of acetylsalicylic acid tablets

M Pishnamazi, J Iqbal, S Shirazian, GM Walker… - International journal of …, 2019 - Elsevier
The main focus of this paper is on the improvement of formulations utilising non-
conventional bio-based excipients to improve tablet release rates. Two different formulations …

Cinnamyl O-amine functionalized chitosan as a new excipient in direct compressed tablets with improved drug delivery

G Ren, C Clancy, TM Tamer, B Schaller… - International journal of …, 2019 - Elsevier
The use of chitosan as a potential excipient in pharmaceutical formulations for the delivery of
drugs produced via direct compression tableting has been investigated. Chitosan, N …

Improving anticancer activity of chrysin using tumor microenvironment pH-responsive and self-assembled nanoparticles

AK Jangid, R Solanki, S Patel, K Medicherla… - ACS …, 2022 - ACS Publications
Chrysin is a natural bioactive compound with potential biological activities. However,
unfavorable physicochemical properties of native chrysin make it difficult to achieve good …