Erythropoietin receptor response circuits

DM Wojchowski, P Sathyanarayana… - Current opinion in …, 2010 - journals.lww.com
Summary As Current Opinion, this monograph seeks to summarize, and provoke, new
EPO/EPOR action concepts. Specific problems addressed include: beyond (and before) …

Erythropoietin stimulates tumor growth via EphB4

S Pradeep, J Huang, EM Mora, AM Nick, MS Cho… - Cancer cell, 2015 - cell.com
While recombinant human erythropoietin (rhEpo) has been widely used to treat anemia in
cancer patients, concerns about its adverse effects on patient survival have emerged. A lack …

Effects of intravitreal erythropoietin therapy for patients with chronic and progressive diabetic macular edema

W Li, SH Sinclair, GT Xu - Ophthalmic Surgery, Lasers and …, 2010 - journals.healio.com
BACKGROUND AND OBJECTIVE: To determine the effects of intravitreal injections of
erythropoietin in eyes with severe, chronic diabetic macular edema, 5 eyes of 5 patients …

Erythropoietin receptor contributes to melanoma cell survival in vivo

SM Kumar, G Zhang, BC Bastian, MO Arcasoy… - Oncogene, 2012 - nature.com
Erythropoietin (Epo) is widely used clinically to treat anemia associated with various clinical
conditions including cancer. Data from several clinical trials suggest significant adverse …

Association of secondhand smoke exposures with DNA methylation in bladder carcinomas

CS Wilhelm-Benartzi, BC Christensen… - Cancer Causes & …, 2011 - Springer
Background The association between secondhand smoke (SHS) exposure and bladder
cancer is inconclusive. Epigenetic alterations in bladder tumors have been linked to primary …

Preoperative evaluation of the oncology patient

SK Sahai, A Zalpour, MA Rozner - Medical Clinics, 2010 - medical.theclinics.com
Although surgery remains the mainstay of cancer care, the advent of multidisciplinary
approaches and the use of multiple therapeutic modalities has increased treatment …

Epigenetic silencing of erythropoietin in human cancers

K Steinmann, AM Richter, RH Dammann - Genes & cancer, 2011 - journals.sagepub.com
The glycoprotein hormone erythropoietin (EPO) is a key regulator in the production of red
blood cells. EPO is produced mainly in the embryonic liver and kidney of adults. Other …

[HTML][HTML] Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic …

SJ Yeh, CA Chang, CW Li, LHC Wang, BS Chen - Oncotarget, 2019 - ncbi.nlm.nih.gov
Non-small-cell lung cancer (NSCLC) is the predominant type of lung cancer in the world.
Lung adenocarcinoma (LADC) and lung squamous cell carcinoma (LSCC) are subtypes of …

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma

A Rozsas, J Berta, L Rojko, LZ Horvath, M Keszthelyi… - PloS one, 2013 - journals.plos.org
Recombinant human erythropoietins (rHuEPOs) are used to treat cancer-related anemia.
Recent preclinical studies and clinical trials, however, have raised concerns about the …

Low or undetectable TPO receptor expression in malignant tissue and cell lines derived from breast, lung, and ovarian tumors

CL Erickson-Miller, K Pillarisetti, J Kirchner… - BMC cancer, 2012 - Springer
Background Numerous efficacious chemotherapy regimens may cause thrombocytopenia.
Thrombopoietin receptor (TPO-R) agonists, such as eltrombopag, represent a novel …