In addition to treating depression, antidepressant drugs are also a first-line treatment for
neuropathic pain, which is pain secondary to lesion or pathology of the nervous system …

Cell type-specific interfaces within living animals will be invaluable for achieving
communication with identifiable cells over the long term, enabling applications across many …

Chronic pain produces psychologic distress, which often leads to mood disorders such as
depression. Co-existing chronic pain and depression pose a serious socio-economic …

Chronic pain aggravates cardiovascular injury via incompletely understood mechanisms.
While melatonin may participate in the pathophysiological process of chronic pain, its …

Chronic pain often develops severe mood changes such as depression. However, how
chronic pain leads to depression remains elusive and the mechanisms determining …

Background Depression is frequently associated with chronic pain or chronic stress. Among
cortical areas, the anterior cingulate cortex (ACC, areas 24a and 24b) appears to be …

The hypothalamic neuropeptide oxytocin (OT) exerts prominent analgesic effects via central
and peripheral action. However, the precise analgesic pathways recruited by OT are largely …

The pathogenesis of neuropathic pain (NP) is characterized by an increased
responsiveness of nociceptive neurons in the nervous system. However, the molecular …

Animal models of pain consist of modeling a pain-like state and measuring the consequent
behavior. The first animal models of neuropathic pain (NP) were developed in rodents with a …

Neuropathic pain is a common health problem resulting in exacerbated response to noxious
and non noxious stimuli, as well as impaired emotional and cognitive responses …