Background Prolonged and overlapping phases of wound healing in diabetes are mainly
due to the redox imbalance resulting in the chronicity of the wound. Photobiomodulation …

Background Legalization of cannabis encourages the development of specific cultivars to
treat disease such as neuropathic pain. Because of the large number of cultivars, it is …

Background Clinical management of neuropathic pain, which is pain arising as a
consequence of a lesion or a disease affecting the somatosensory system, partly relies on …

It is well established that early blindness results in brain plasticity and behavioral changes in
both humans and animals. However, only a few studies have examined the effects of …

Neuropathic pain is a chronic pain caused by a lesion or disease affecting the
somatosensory nervous system. To date, no specific treatment has been developed to cure …

Chronic pain occurs with greater frequency in women, with a parallel sexually dimorphic
trend reported in sufferers of many autoimmune diseases. There is a need to continue …

Chronic constriction injuries (CCI) of the sciatic nerve are widely used nerve entrapment
animal models of neuropathic pain. Two common pain behaviors observed following CCI …

Individuals with diabetic foot ulcers have overlapped the inflammatory, proliferative and
remodeling phase, making the tissue vulnerable to delayed healing responses. We aimed to …

Endogenous acetylcholine (ACh) is an important modulator of nociceptive sensory
processing in the spinal cord. An increased level of spinal ACh induces analgesia both in …

Peripheral delta opioid (DOP) receptors are essential for the antiallodynic effect of the
tricyclic antidepressant nortriptyline. However, the population of DOP‐expressing cells …