Prevention and treatment of acute lung injury with time-controlled adaptive ventilation: physiologically informed modification of airway pressure release ventilation
GF Nieman, LA Gatto, P Andrews, J Satalin… - Annals of intensive …, 2020 - Springer
Mortality in acute respiratory distress syndrome (ARDS) remains unacceptably high at
approximately 39%. One of the only treatments is supportive: mechanical ventilation …
approximately 39%. One of the only treatments is supportive: mechanical ventilation …
Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report
HS Kulkarni, JS Lee, JA Bastarache… - American journal of …, 2022 - atsjournals.org
Advancements in methods, technology, and our understanding of the pathobiology of lung
injury have created the need to update the definition of experimental acute lung injury (ALI) …
injury have created the need to update the definition of experimental acute lung injury (ALI) …
Monitoring lung injury severity and ventilation intensity during mechanical ventilation
Acute respiratory distress syndrome (ARDS) is a severe form of respiratory failure burden by
high hospital mortality. No specific pharmacologic treatment is currently available and its …
high hospital mortality. No specific pharmacologic treatment is currently available and its …
Lung response to prone positioning in mechanically-ventilated patients with COVID-19
Background Prone positioning improves survival in moderate-to-severe acute respiratory
distress syndrome (ARDS) unrelated to the novel coronavirus disease (COVID-19). This …
distress syndrome (ARDS) unrelated to the novel coronavirus disease (COVID-19). This …
A physiologically informed strategy to effectively open, stabilize, and protect the acutely injured lung
GF Nieman, H Al-Khalisy, M Kollisch-Singule… - Frontiers in …, 2020 - frontiersin.org
Acute respiratory distress syndrome (ARDS) causes a heterogeneous lung injury and
remains a serious medical problem, with one of the only treatments being supportive care in …
remains a serious medical problem, with one of the only treatments being supportive care in …
Prone positioning for acute hypoxemic respiratory failure and ARDS: a review
Prone positioning is an immediately accessible, readily implementable intervention that was
proposed initially as a method for improvement in gas exchange> 50 years ago. Initially …
proposed initially as a method for improvement in gas exchange> 50 years ago. Initially …
Dynamic bedside assessment of the physiologic effects of prone position in acute respiratory distress syndrome patients by electrical impedance tomography
F Dalla Corte, T Mauri, E Spinelli, M Lazzeri… - Minerva …, 2020 - air.unimi.it
Background: Prone position (PP) improves acute respiratory distress syndrome (ARDS)
survival by reducing the risk of ventilation-induced lung injury. However, inter-individual …
survival by reducing the risk of ventilation-induced lung injury. However, inter-individual …
Imaging the injured lung: mechanisms of action and clinical use
Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure
characterized by massive and heterogeneously distributed loss of lung aeration caused by …
characterized by massive and heterogeneously distributed loss of lung aeration caused by …
The time-controlled adaptive ventilation protocol: mechanistic approach to reducing ventilator-induced lung injury
M Kollisch-Singule, P Andrews, J Satalin… - European …, 2019 - Eur Respiratory Soc
Airway pressure release ventilation (APRV) is a ventilator mode that has previously been
considered a rescue mode, but has gained acceptance as a primary mode of ventilation. In …
considered a rescue mode, but has gained acceptance as a primary mode of ventilation. In …
Diminishing efficacy of prone positioning with late application in evolving lung injury
OBJECTIVES: It is not known how lung injury progression during mechanical ventilation
modifies pulmonary responses to prone positioning. We compared the effects of prone …
modifies pulmonary responses to prone positioning. We compared the effects of prone …