Background Despite multiple rigorous observational studies documenting the association
between positive mental health outcomes and access to puberty blockers, hormone therapy …

The paradigm of pediatric drug development has been evolving in a “carrot-and-stick”-based
tactic to address population-specific issues. However, the off-label prescription of adult …

Background Since 2016 trans people in the UK, and particularly trans children, have
experienced a sustained and escalating campaign to roll back trans freedoms, rights and …

Off-label prescribing is widespread among pediatricians, and it is unlikely that this trend will
soon be bound by a uniform legal framework. This is necessitated by the fact that there are …

Awareness related to the risk/benefit profile of therapies used in paediatric and elderly
patients is limited. We carried out a study, called the MEAP 3.0 study, to collect and analyse …

The last year witnessed several significant shortages of key medicines and other products
for children, including children's formulations of acetaminophen and ibuprofen as well as …

Background Children are often treated off-label and are at a disadvantage in
pharmacotherapy. The aim of this study was to implement and evaluate a quality assurance …

Background: Information regarding off-label and unlicensed medicine use among South
African children is limited. This is a concern as the prescribing of off-label and unlicensed …

Objectives This study aimed to investigate and provide insight into the prevalence and
patterns of off-label drug use in the pediatric population from the perspective of community …

This review comprehensively explores pediatric capnography, a vital tool in contemporary
respiratory monitoring. The overview encompasses the foundational principles of …