Microtubule-associated proteins (MAPs) were initially discovered as proteins that bind to
and stabilize microtubules. Today, an ever-growing number of MAPs reveals a more …

Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …

The interior of a living cell is a crowded, heterogenuous, fluctuating environment. Hence, a
major challenge in modeling intracellular transport is to analyze stochastic processes within …

The remarkable ability of a single axon to extend multiple branches and form terminal arbors
enables vertebrate neurons to integrate information from divergent regions of the nervous …

During CNS development, oligodendrocytes wrap their plasma membrane around axons to
generate multilamellar myelin sheaths. To drive growth at the leading edge of myelin at the …

Motile growth cones lead growing axons through developing tissues to synaptic targets.
These behaviors depend on the organization and dynamics of actin filaments that fill the …

This review highlights recent trends towards the development of in vitro multicellular systems
with definite architectures, or “organs on chips”. First, the chemical composition and …

The graded distribution of morphogens underlies many of the tissue patterns that form
during development. How morphogens disperse from a localized source and how gradients …

Biofabrication techniques have endeavored to improve the regeneration of the peripheral
nervous system (PNS), but nothing has surpassed the performance of current clinical …

The axon is the single long fiber that extends from the neuron and transmits electrical
signals away from the cell body. The neuronal cytoskeleton, composed of microtubules …