New therapies for hepatocellular carcinoma

MA Avila, C Berasain, B Sangro, J Prieto - Oncogene, 2006 - nature.com
Hepatocellular carcinoma (HCC), one of the most common cancers worldwide, is often
diagnosed at an advanced stage when most potentially curative therapies such as resection …

Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells

DA Ingram, NM Caplice, MC Yoder - Blood, 2005 - ashpublications.org
The field of vascular biology has been stimulated by the concept that circulating endothelial
progenitor cells (EPCs) may play a role in neoangiogenesis (postnatal vasculogenesis) …

Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels

S Nishimura, I Manabe, M Nagasaki, Y Hosoya… - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—The expansion of adipose tissue mass seen in obesity involves both
hyperplasia and hypertrophy of adipocytes. However, little is known about how adipocytes …

VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at site of tumor neovascularization

B Li, EE Sharpe, AB Maupin, AA Teleron… - The FASEB …, 2006 - Wiley Online Library
There are growing data to suggest that tissue hypoxia represents a critical force that drives
adult vasculogenesis. Vascular endothelial growth factor (VEGF) expression is dramatically …

Successful stem cell therapy using umbilical cord blood-derived multipotent stem cells for Buerger's disease and ischemic limb disease animal model

SW Kim, H Han, GT Chae, SH Lee, S Bo, JH Yoon… - Stem …, 2006 - academic.oup.com
Buerger's disease, also known as thromboangiitis obliterans, is a nonatherosclerotic,
inflammatory, vasoocclusive disease. It is characterized pathologically as a panangiitis of …

Endothelial dysfunction: a key to the pathophysiology and natural history of peripheral arterial disease?

G Brevetti, V Schiano, M Chiariello - Atherosclerosis, 2008 - Elsevier
Dysfunctional endothelium plays a crucial role in all stages of atherosclerosis and thus the
accurate assessment of this organ is a valuable tool, especially if such assessments are …

Tissue engineering of blood vessels

MS Baguneid, AM Seifalian, HJ Salacinski… - Journal of British …, 2006 - academic.oup.com
Background Tissue engineering techniques have been employed successfully in the
management of wounds, burns and cartilage repair. Current prosthetic alternatives to …

Endothelial progenitor cells as a new agent contributing to vascular repair

E Miller-Kasprzak, PP Jagodziński - Archivum immunologiae et therapiae …, 2007 - Springer
A special type of stem cells, defined as endothelial progenitor cells (EPCs), has been found
in the bone marrow and peripheral blood. These EPCs are incorporated into injured vessels …

Sphingosine-1-Phosphate Stimulates the Functional Capacity of Progenitor Cells by Activation of the CXCR4-Dependent Signaling Pathway via the S1P3 Receptor

DH Walter, U Rochwalsky, J Reinhold… - … , and vascular biology, 2007 - Am Heart Assoc
Objective—Sphingosine-1-phosphate (S1P) is a bioactive lipid, which influences migration
and proliferation of endothelial cells through activation of S1P receptors and has been …

Characteristics of infantile hemangiomas as clues to pathogenesis: does hypoxia connect the dots?

BA Drolet, IJ Frieden - Archives of dermatology, 2010 - jamanetwork.com
INFANTILE HEMANGIOMAS (IHS) ARE THE MOST common tumor of infancy. Their unique
clini-cal characteristics, including emergence after birth as a rapidly growing plaque with a …