NAFLD: mechanisms, treatments, and biomarkers
F Nassir - Biomolecules, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …
Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …
disease worldwide and is strongly associated with the presence of oxidative stress …
Dietary carbohydrates and fats in nonalcoholic fatty liver disease
H Yki-Järvinen, PK Luukkonen, L Hodson… - Nature reviews …, 2021 - nature.com
The global prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease
GI Smith, M Shankaran, M Yoshino… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND An increase in intrahepatic triglyceride (IHTG) is the hallmark feature of
nonalcoholic fatty liver disease (NAFLD) and is decreased by weight loss. Hepatic de novo …
nonalcoholic fatty liver disease (NAFLD) and is decreased by weight loss. Hepatic de novo …
Nonalcoholic fatty liver disease 2020: the state of the disease
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, with a worldwide
prevalence of 25%. In the United States, NAFLD and its subtype, nonalcoholic …
prevalence of 25%. In the United States, NAFLD and its subtype, nonalcoholic …
Compromised hepatic mitochondrial fatty acid oxidation and reduced markers of mitochondrial turnover in human NAFLD
MP Moore, RP Cunningham, GM Meers… - …, 2022 - Wiley Online Library
Background and Aims NAFLD and its more‐advanced form, steatohepatitis (NASH), is
associated with obesity and is an independent risk factor for cardiovascular, liver‐related …
associated with obesity and is an independent risk factor for cardiovascular, liver‐related …
The crucial role and mechanism of insulin resistance in metabolic disease
X Zhao, X An, C Yang, W Sun, H Ji… - Frontiers in endocrinology, 2023 - frontiersin.org
Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …
[HTML][HTML] Mechanisms of insulin action and insulin resistance
MC Petersen, GI Shulman - Physiological reviews, 2018 - journals.physiology.org
The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of
research into insulin action and resistance has issued. In the intervening century, some …
research into insulin action and resistance has issued. In the intervening century, some …
Mechanisms of NAFLD development and therapeutic strategies
SL Friedman, BA Neuschwander-Tetri, M Rinella… - Nature medicine, 2018 - nature.com
There has been a rise in the prevalence of nonalcoholic fatty liver disease (NAFLD),
paralleling a worldwide increase in diabetes and metabolic syndrome. NAFLD, a continuum …
paralleling a worldwide increase in diabetes and metabolic syndrome. NAFLD, a continuum …
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is currently the world's most common liver
disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic …
disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic …