[HTML][HTML] Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke

L Wang, X Zhang, X Xiong, H Zhu, R Chen, S Zhang… - Antioxidants, 2022 - mdpi.com
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …

[HTML][HTML] TGF-β in hepatic stellate cell activation and liver fibrogenesis—updated 2019

B Dewidar, C Meyer, S Dooley, N Meindl-Beinker - Cells, 2019 - mdpi.com
Liver fibrosis is an advanced liver disease condition, which could progress to cirrhosis and
hepatocellular carcinoma. To date, there is no direct approved antifibrotic therapy, and …

Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues

M Parola, M Pinzani - Molecular aspects of medicine, 2019 - Elsevier
The progression of chronic liver diseases (CLD), irrespective of etiology, involves chronic
parenchymal injury, persistent activation of inflammatory response as well as sustained …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Inorganic nanoparticles in clinical trials and translations

H Huang, W Feng, Y Chen, J Shi - Nano today, 2020 - Elsevier
The development and application of nanotechnology-related knowledge and tools in
modern medicine has been showing great potentials in elevating human's living standards …

Mechanisms of hepatic stellate cell activation

T Tsuchida, SL Friedman - Nature reviews Gastroenterology & …, 2017 - nature.com
Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular
matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic …

Cancer treatment through nanoparticle-facilitated fenton reaction

H Ranji-Burachaloo, PA Gurr, DE Dunstan, GG Qiao - ACS nano, 2018 - ACS Publications
Currently, cancer is the second largest cause of death worldwide and has reached critical
levels. In spite of all the efforts, common treatments including chemotherapy, photodynamic …

[HTML][HTML] A multicenter randomized-controlled trial of hypothermic oxygenated perfusion (HOPE) for human liver grafts before transplantation

A Schlegel, M Mueller, X Muller, J Eden… - Journal of …, 2023 - Elsevier
Background & Aims Machine perfusion is a novel method intended to optimize livers before
transplantation. However, its effect on morbidity within a 1-year period after transplantation …

[HTML][HTML] Diverse roles of mitochondria in ischemic stroke

JL Yang, S Mukda, SD Chen - Redox biology, 2018 - Elsevier
Stroke is the leading cause of adult disability and mortality in most developing and
developed countries. The current best practices for patients with acute ischemic stroke …

Combating oxidative stress and inflammation in COVID‐19 by molecular hydrogen therapy: mechanisms and perspectives

D Alwazeer, FFC Liu, XY Wu… - Oxidative Medicine and …, 2021 - Wiley Online Library
COVID‐19 is a widespread global pandemic with nearly 185 million confirmed cases and
about four million deaths. It is caused by an infection with the severe acute respiratory …