MicroRNAs (miRNAs), a class of small noncoding RNA molecules, have been recognized as
key post-transcriptional regulators associated with a multitude of human diseases. Global …

A growing number of evidences from clinical and preclinical studies have shown that
dysregulation of microRNA (miRNA) function contributes to the progression of cancer and …

Background Endometriosis, a chronic disease that afflicts millions of women worldwide, has
traditionally been diagnosed by laparoscopic surgery. This diagnostic barrier delays …

The human genome is 'pervasively transcribed'leading to a complex array of non-coding
RNAs (ncRNAs) that far outnumber coding mRNAs. ncRNAs have regulatory roles in …

Emerging evidence has revealed that miRNAs could upregulate the expression levels of
target genes. However, the molecular mechanism underlying upregulation of targets …

MicroRNA‐221/222 (miRNA‐221/222, miR‐221/222) is a noncoding microRNA which is
widely distributed in eukaryotic organisms and deeply involved in the posttranscriptional …

Background Insulin-like growth factor-1 receptor (IGF-1R) is a well-studied oncogenic factor
that promotes cell proliferation and energy metabolism and is overexpressed in numerous …

Ovarian cancer is the most aggressive of all gynaecological malignancies and is the leading
cause of cancer-associated mortality worldwide. Over the recent years, there has been a …

Endometrial cancer (EC) is the most common gynecological cancer, with annual incidence
rates in Western countries ranging between 15 and 25 per 100 000 women. About 15% to …

Increasing evidence showed that long noncoding RNAs (lncRNAs) played an important role
in the occurrence and development of tumors. To date, lncRNA small nucleolar RNA host …