The Growth Arrest and DNA Damage-inducible 45 (GADD45) proteins have been implicated
in regulation of many cellular functions including DNA repair, cell cycle control, senescence …

The Gadd45 proteins have been intensively studied, in view of their important role in key
cellular processes. Indeed, the Gadd45 proteins stand at the crossroad of the cell fates by …

Motivation: The elucidation of biological pathways enriched with differentially expressed
genes has become an integral part of the analysis and interpretation of microarray data …

Gadd45 proteins, including Gadd45a, Gadd45b, and Gadd45g, have been implicated in
stress signaling in response to physiological and environmental stress, including oncogenic …

We investigated the mechanism of action of LBH589, a novel broad-spectrum HDAC
inhibitor belonging to the hydroxamate class, in Philadelphia chromosome–negative (Ph−) …

Gadd45 genes have been implicated in stress signaling responses to various physiological
or environmental stressors, resulting in cell cycle arrest, DNA repair, cell survival and …

Furan is a widely used industrial chemical and a contaminant in heated foods. Chronic furan
exposure causes cholangiocarcinoma and hepatocellular tumors in rats at doses of 2 mg/kg …

The Gadd45 family of proteins, which includes α, β, and γ isoforms, has recently been shown
to play a role in the G2/M cell cycle checkpoint in response to DNA damage; however, the …

Growth arrest and DNA damage 45G (GADD45G), a stress sensor with multiple implications
in various biological processes, is down-regulated in a broad spectrum of cancers. However …

The growth arrest and DNA damage-inducible 45 (Gadd45) proteins are a group of critical
signal transducers that are involved in regulations of many cellular functions. Accumulated …