Abstract The Receptor for Activated C Kinase 1 (RACK1) is a member of the tryptophan-
aspartate repeat (WD-repeat) family of proteins and shares significant homology to the β …

Molecular mechanisms underlying sarcopenia, the age-related loss of skeletal muscle mass
and function, remain unclear. To identify molecular changes that correlated best with …

Approximately 66% of the patients with rheumatoid arthritis (RA) have significant loss of cell
mass (rheumatoid cachexia), mainly of skeletal muscle (rheumatoid sarcopenia) …

Luchuan pig is a typical obese pig breed in China, and the diameter and area of its
longissimus dorsi muscle fibers are significantly smaller than those of Duroc (lean) pig …

Important insights concerning the molecular basis of skeletal muscle disuse-atrophy and
aging related muscle loss have been obtained in cell culture and animal models, but these …

Spaceflight conditions have a significant impact on a number of physiological functions due
to psychological stress, radiation, and reduced gravity. To explore the effect of the flight …

A unique property of skeletal muscle is its ability to adapt its mass to changes in activity.
Inactivity, as in disuse or aging, causes atrophy, the loss of muscle mass and strength …

Background Sarcopenia is defined as the age‐related loss of skeletal muscle mass and
function. While all humans lose muscle with age, 2–5% of elderly adults develop functional …

Non-small-cell lung cancer (NSCLC) is a deadly disease due to lack of effective diagnosis
biomarker and therapeutic target. Much effort has been made in defining gene defects in …

Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disorder characterized by
ptosis, dysphagia and proximal limb weakness. Autosomal-dominant OPMD is caused by a …