Epigenetics and genetics of hepatoblastoma: linkage and treatment
L Zhu, W Zheng, Q Gao, T Chen, Z Pan, W Cui… - Frontiers in …, 2022 - frontiersin.org
Hepatoblastoma is a malignant embryonal tumor with multiple differentiation modes and is
the clearest liver malignancy in children. However, little is known about genetic and …
the clearest liver malignancy in children. However, little is known about genetic and …
Preneoplastic liver colonization by 11p15. 5 altered mosaic cells in young children with hepatoblastoma
J Pilet, TZ Hirsch, B Gupta, A Roehrig… - Nature …, 2023 - nature.com
Pediatric liver tumors are very rare tumors with the most common diagnosis being
hepatoblastoma. While hepatoblastomas are predominantly sporadic, around 15% of cases …
hepatoblastoma. While hepatoblastomas are predominantly sporadic, around 15% of cases …
Cancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development
S Nirgude, NSS Naveh, SL Kavari, EM Traxler… - British Journal of …, 2024 - nature.com
Background Wilms tumor (WT) exhibits structural and epigenetic changes at chromosome
11p15, which also cause Beckwith-Wiedemann Syndrome (BWS). Children diagnosed with …
11p15, which also cause Beckwith-Wiedemann Syndrome (BWS). Children diagnosed with …
Dysfunction in IGF2R Pathway and Associated Perturbations in Autophagy and WNT Processes in Beckwith–Wiedemann Syndrome Cell Lines
S Pileggi, EA Colombo, S Ancona, R Quadri… - International Journal of …, 2024 - mdpi.com
Beckwith–Wiedemann Syndrome (BWS) is an imprinting disorder characterized by
overgrowth, stemming from various genetic and epigenetic changes. This study delves into …
overgrowth, stemming from various genetic and epigenetic changes. This study delves into …
Performance of Tumor Surveillance for Children With Cancer Predisposition
A Blake, MR Perrino, CE Morin, L Taylor… - JAMA …, 2024 - jamanetwork.com
Importance Pediatric oncology patients are increasingly recognized as having an underlying
cancer predisposition syndrome (CPS). Surveillance is often recommended to detect new …
cancer predisposition syndrome (CPS). Surveillance is often recommended to detect new …
Occurrence of Hepatoblastomas in Patients with Beckwith–Wiedemann Spectrum (BWSp)
SD Klein, M DeMarchis, RL Linn, SP MacFarland… - Cancers, 2023 - mdpi.com
Simple Summary Beckwith–Wiedemann syndrome (BWS) is an overgrowth and cancer
predisposition disorder that is associated with increased risk of hepatoblastoma (HB), a liver …
predisposition disorder that is associated with increased risk of hepatoblastoma (HB), a liver …
Therapeutic approaches to imprinting diseases
H Sassi, LG Rousseau, J Grill, E Rouleau - Epigenetics in Human Disease, 2024 - Elsevier
Genomic imprinting disorders are rare diseases that arise from the disruption of genetic or
epigenetic mechanisms, within monoallelic expressed genes from a parental-specific allele …
epigenetic mechanisms, within monoallelic expressed genes from a parental-specific allele …
A rare case of hepatoblastoma in a syndromic child with a de novo germline JAG1 mutation
GD Dangoni, ACB Teixeira, TF Aguiar… - Pediatric blood & …, 2023 - pubmed.ncbi.nlm.nih.gov
A rare case of hepatoblastoma in a syndromic child with a de novo germline JAG1 mutation A
rare case of hepatoblastoma in a syndromic child with a de novo germline JAG1 mutation …
rare case of hepatoblastoma in a syndromic child with a de novo germline JAG1 mutation …