The reactive oxygen species in macrophage polarization: reflecting its dual role in progression and treatment of human diseases

HY Tan, N Wang, S Li, M Hong… - … medicine and cellular …, 2016 - Wiley Online Library
High heterogeneity of macrophage is associated with its functions in polarization to different
functional phenotypes depending on environmental cues. Macrophages remain in balanced …

Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress

AA Shvedova, A Pietroiusti, B Fadeel… - Toxicology and applied …, 2012 - Elsevier
Nanotechnologies are emerging as highly promising technologies in many sectors in the
society. However, the increasing use of engineered nanomaterials also raises concerns …

Respiratory risks from household air pollution in low and middle income countries

SB Gordon, NG Bruce, J Grigg, PL Hibberd… - The lancet Respiratory …, 2014 - thelancet.com
A third of the world's population uses solid fuel derived from plant material (biomass) or coal
for cooking, heating, or lighting. These fuels are smoky, often used in an open fire or simple …

Redox control of inflammation in macrophages

B Brüne, N Dehne, N Grossmann, M Jung… - Antioxidants & redox …, 2013 - liebertpub.com
Macrophages are present throughout the human body, constitute important immune effector
cells, and have variable roles in a great number of pathological, but also physiological …

Alcohol, oxidative stress and free radical damage

E Albano - Proceedings of the nutrition society, 2006 - cambridge.org
The involvement of free radical mechanisms in the pathogenesis of alcoholic liver disease
(ALD) is demonstrated by the detection of lipid peroxidation markers in the liver and the …

Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease

DA Butterfield, MLB Lange, R Sultana - … BBA)-Molecular and Cell Biology of …, 2010 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disorder. A number of
hypotheses have been proposed to explain AD pathogenesis. One such hypothesis …

Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine

VE Kagan, GG Borisenko, YY Tyurina, VA Tyurin… - Free Radical Biology …, 2004 - Elsevier
The primary life-supporting function of cytochrome c (cyt c) is control of cellular energetic
metabolism as a mobile shuttle in the electron transport chain of mitochondria. Recently, cyt …

Tocopherols and tocotrienols in membranes: a critical review

J Atkinson, RF Epand, RM Epand - Free radical biology and medicine, 2008 - Elsevier
The familiar role of tocols (tocopherols and tocotrienols) as lipid-soluble chain-terminating
inhibitors of lipid peroxidation is currently in the midst of a reinterpretation. New biological …

Oxidative mechanisms in the pathogenesis of alcoholic liver disease

E Albano - Molecular aspects of Medicine, 2008 - Elsevier
Although the capacity of ethanol to induce oxidative stress in the liver is well established, the
mechanisms by which oxidative damage contributes to the pathogenesis of alcoholic liver …

Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory

MK Chang, CJ Binder, YI Miller… - The Journal of …, 2004 - rupress.org
Oxidation of low density lipoprotein (LDL) generates a variety of oxidatively modified lipids
and lipid-protein adducts that are immunogenic and proinflammatory, which in turn …