Recent trends in application of chemometric methods for GC-MS and GCŨGC-MS-based metabolomic studies

N Feizi, FS Hashemi-Nasab, F Golpelichi… - TrAC Trends in …, 2021 - Elsevier
Metabolomics is the science of studying small molecules (metabolites) in biological systems
with the aim of getting insight into cells, biofluids and organisms. Chemometric methods are …

The toxicity of nanoparticles and their interaction with cells: an in vitro metabolomic perspective

M Awashra, P Młynarz - Nanoscale Advances, 2023 - pubs.rsc.org
Nowadays, nanomaterials (NMs) are widely present in daily life due to their significant
benefits, as demonstrated by their application in many fields such as biomedicine …

Interactions between graphene oxide and plant cells: Regulation of cell morphology, uptake, organelle damage, oxidative effects and metabolic disorders

X Hu, K Lu, L Mu, J Kang, Q Zhou - Carbon, 2014 - Elsevier
In various fields, much attention has been paid to graphene oxide (GO) nanosheets as a
novel engineered nanomaterial. Understanding the interactions between GO and plant cells …

Role of omics techniques in the toxicity testing of nanoparticles

E Fröhlich - Journal of nanobiotechnology, 2017 - Springer
Nanotechnology is regarded as a key technology of the twenty-first century. Despite the
many advantages of nanotechnology it is also known that engineered nanoparticles (NPs) …

Investigating the effect of Ti3C2 (MXene) nanosheet on human umbilical vein endothelial cells via a combined untargeted and targeted metabolomics approach

D Zhang, W Zheng, X Li, A Li, N Ye, L Zhang, Y Liu… - Carbon, 2021 - Elsevier
Ti 3 C 2 is the first member of two-dimensional (2D) transition metal carbide or carbonitride
(MXene) with excellent photothermal effect in disease treatment on an animal model, which …

Elevated temperature decreases cardiovascular toxicity of nanoplastics but adds to their lethality: A case study during zebrafish (Danio rerio) development

Z Duan, J Wang, H Zhang, Y Wang, Y Chen… - Journal of Hazardous …, 2023 - Elsevier
To highlight the key role of global warming on the toxicity of contaminants, the
cardiovascular toxicity of nanoparticles (NPs) was estimated in developing zebrafish (Danio …

Copper oxide nanoparticle toxicity profiling using untargeted metabolomics

MSP Boyles, C Ranninger, R Reischl, M Rurik… - Particle and fibre …, 2015 - Springer
Background The rapidly increasing number of engineered nanoparticles (NPs), and
products containing NPs, raises concerns for human exposure and safety. With this …

Kdm6a deficiency in microglia/macrophages epigenetically silences Lcn2 expression and reduces photoreceptor dysfunction in diabetic retinopathy

Y Wen, X Chen, H Feng, X Wang, X Kang, P Zhao… - Metabolism, 2022 - Elsevier
Diabetic retinopathy (DR) is one of the leading causes of severe visual impairment
worldwide. However, the role of adaptive immune inflammation driven by microglia …

Quantitative assessment of nanoparticle surface hydrophobicity and its influence on pulmonary biocompatibility

MC Jones, SA Jones, Y Riffo-Vasquez, D Spina… - Journal of Controlled …, 2014 - Elsevier
To date, the role of nanoparticle surface hydrophobicity has not been investigated
quantitatively in relation to pulmonary biocompatibility. A panel of nanoparticles spanning …

Cellular response of Chlorella pyrenoidosa to oxidized multi-walled carbon nanotubes

L Zhang, C Lei, K Yang, JC White, D Lin - Environmental Science …, 2018 - pubs.rsc.org
Although many reports have demonstrated significant toxicity upon exposure to carbon
nanotubes (CNTs), the interaction of these materials with microalgae and the resulting …