Mechanisms and models in heart failure: the biomechanical model and beyond
DL Mann, MR Bristow - Circulation, 2005 - Am Heart Assoc
resultant striking increase in morbidity and mortality. The transition to symptomatic heart
failure is accompanied by further activation of neurohormonal and cytokine systems, as well …
failure is accompanied by further activation of neurohormonal and cytokine systems, as well …
Unchain my heart: the scientific foundations of cardiac repair
S Dimmeler, AM Zeiher… - The Journal of clinical …, 2005 - Am Soc Clin Investig
In humans, the biological limitations to cardiac regenerative growth create both a clinical
imperative—to offset cell death in acute ischemic injury and chronic heart failure—and a …
imperative—to offset cell death in acute ischemic injury and chronic heart failure—and a …
A phase I clinical trial of the treatment of Crohn's fistula by adipose mesenchymal stem cell transplantation
D García-Olmo, M García-Arranz, D Herreros… - Diseases of the colon & …, 2005 - Springer
PURPOSE The effective management of fistulas in patients with Crohn's disease presents
an extremely challenging problem. Mesenchymal adult stem cells extracted from certain …
an extremely challenging problem. Mesenchymal adult stem cells extracted from certain …
Bone marrow–derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation
Recent studies have suggested that bone marrow cells might possess a much broader
differentiation potential than previously appreciated. In most cases, the reported efficiency of …
differentiation potential than previously appreciated. In most cases, the reported efficiency of …
Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction
F Fernández-Avilés, JA San Román… - Circulation …, 2004 - Am Heart Assoc
Bone marrow mononuclear cells (BMCs) from 20 patients with extensive reperfused
myocardial infarction (MI) were used to assess their myocardial regenerative capability “in …
myocardial infarction (MI) were used to assess their myocardial regenerative capability “in …
Leukocytosis and ischemic vascular disease morbidity and mortality: is it time to intervene?
BS Coller - Arteriosclerosis, thrombosis, and vascular biology, 2005 - Am Heart Assoc
The association between leukocytosis and increased morbidity and mortality of ischemic
vascular disease has been observed for more than half a century, and recent studies in> …
vascular disease has been observed for more than half a century, and recent studies in> …
CD14+CD34low Cells With Stem Cell Phenotypic and Functional Features Are the Major Source of Circulating Endothelial Progenitors
Endothelial progenitor cells (EPCs) seem to be a promising tool for cell therapy of acute
myocardial infarction, but their nature is still unclear. We show here that EPCs obtainable …
myocardial infarction, but their nature is still unclear. We show here that EPCs obtainable …
[HTML][HTML] Endothelial progenitor cells in atherosclerosis
F Du, J Zhou, R Gong, X Huang… - … in bioscience: a …, 2012 - ncbi.nlm.nih.gov
Endothelial progenitor cells (EPCs) are involved in the maintenance of endothelial
homoeostasis and in the process of new vessel formation. Experimental and clinical studies …
homoeostasis and in the process of new vessel formation. Experimental and clinical studies …
Bone marrow stem cell transplantation for cardiac repair
Cardiomyocytes respond to physiological or pathological stress only by hypertrophy and not
by an increase in the number of functioning cardiomyocytes. However, recent evidence …
by an increase in the number of functioning cardiomyocytes. However, recent evidence …
Granulocyte Colony-Stimulating Factor–Mobilized Circulating c-Kit+/Flk-1+ Progenitor Cells Regenerate Endothelium and Inhibit Neointimal Hyperplasia After …
M Takamiya, M Okigaki, D Jin, S Takai… - … , and vascular biology, 2006 - Am Heart Assoc
Background—Granulocyte colony-stimulating factor (G-CSF) treatment was shown to inhibit
neointimal formation of balloon-injured vessels, whereas neither the identification of …
neointimal formation of balloon-injured vessels, whereas neither the identification of …