It is estimated that 2% to 3% of the population are currently prescribed systemic or topical
glucocorticoid treatment. The potent anti-inflammatory action of glucocorticoids to deliver …

Glucocorticoids remain widely used for many medical conditions, and fractures are the most
serious common adverse event related to long-term glucocorticoid use. Glucocorticoid …

BACKGROUND: There is little knowledge about clinical variables associated with vitamin D
(VitD) insufficiency in asthmatic children. OBJECTIVE: We sought to investigate disease …

Context Recent studies of inhaled corticosteroid (ICS) therapy for managing stable chronic
obstructive pulmonary disease (COPD) have yielded conflicting results regarding survival …

Background Osteoporosis is common in patients with COPD, but its prevalence and
progression are not well characterized. Concerns have been raised over the possible …

Smoking-induced lung diseases were extremely rare prior to the 20th century. With
commercialization and introduction of machine-made cigarettes, worldwide use skyrocketed …

OBJECTIVE. Systemic corticosteroids are known to induce osteoporosis and increase the
risk for fractures in adults and children. Inhaled corticosteroids have been shown to increase …

Background Treatment guidelines recommend the use of inhaled corticosteroids in patients
with asthma who have persistent symptoms and the “stepping down” of therapy to the …

Inhaled corticosteroids (ICS) are now very widely used in high doses in the management of
COPD patients. In sharp contrast to the situation in asthma, ICS provide little or no benefit in …

Glucocorticoids are steroid hormones produced by the adrenal cortex. They have pleiotropic
effects and contribute substantially to the maintenance of resting and stress-related …