Network science of biological systems at different scales: A review
Network science is today established as a backbone for description of structure and function
of various physical, chemical, biological, technological, and social systems. Here we review …
of various physical, chemical, biological, technological, and social systems. Here we review …
Big data in IBD: big progress for clinical practice
IBD is a complex multifactorial inflammatory disease of the gut driven by extrinsic and
intrinsic factors, including host genetics, the immune system, environmental factors and the …
intrinsic factors, including host genetics, the immune system, environmental factors and the …
CD44/CD44v6 a reliable companion in cancer-initiating cell maintenance and tumor progression
Z Wang, K Zhao, T Hackert, M Zöller - Frontiers in cell and …, 2018 - frontiersin.org
Metastasis is the leading cause of cancer death, tumor progression proceeding through
emigration from the primary tumor, gaining access to the circulation, leaving the circulation …
emigration from the primary tumor, gaining access to the circulation, leaving the circulation …
TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness
S Rossi, M Cordella, C Tabolacci, G Nassa… - Journal of Experimental …, 2018 - Springer
Background Melanoma aggressiveness determines its growth and metastatic potential. This
study aimed at identifying new molecular pathways controlling melanoma cell malignancy …
study aimed at identifying new molecular pathways controlling melanoma cell malignancy …
Research hotspot and trend analysis in the diagnosis of inflammatory bowel disease: a machine learning bibliometric analysis from 2012 to 2021
C Liu, R Yu, J Zhang, S Wei, F Xue, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Aims This study aimed to conduct a bibliometric analysis of the relevant literature on the
diagnosis of inflammatory bowel disease (IBD), and show its current status, hot spots, and …
diagnosis of inflammatory bowel disease (IBD), and show its current status, hot spots, and …
Inflammatory bowel disease biomarkers of human gut microbiota selected via different feature selection methods
The tremendous boost in next generation sequencing and in the “omics” technologies
makes it possible to characterize the human gut microbiome—the collective genomes of the …
makes it possible to characterize the human gut microbiome—the collective genomes of the …
From isles of Königsberg to islets of Langerhans: examining the function of the endocrine pancreas through network science
Islets of Langerhans are multicellular microorgans located in the pancreas that play a central
role in whole-body energy homeostasis. Through secretion of insulin and other hormones …
role in whole-body energy homeostasis. Through secretion of insulin and other hormones …
Network pharmacology of adaptogens in the assessment of their pleiotropic therapeutic activity
A Panossian, T Efferth - Pharmaceuticals, 2022 - mdpi.com
The reductionist concept, based on the ligand–receptor interaction, is not a suitable model
for adaptogens, and herbal preparations affect multiple physiological functions, revealing …
for adaptogens, and herbal preparations affect multiple physiological functions, revealing …
Whither systems medicine?
R Apweiler, T Beissbarth, MR Berthold… - … & molecular medicine, 2018 - nature.com
New technologies to generate, store and retrieve medical and research data are inducing a
rapid change in clinical and translational research and health care. Systems medicine is the …
rapid change in clinical and translational research and health care. Systems medicine is the …
The scope of big data in one medicine: unprecedented opportunities and challenges
Advances in high-throughput molecular biology and electronic health records (EHR),
coupled with increasing computer capabilities have resulted in an increased interest in the …
coupled with increasing computer capabilities have resulted in an increased interest in the …