Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes
Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …
biochemical processes leading to elevated production of reactive oxygen species (ROS) …
Reactive oxygen species (ROS)-based nanomedicine
B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis
Although mutations in mitochondrial-associated genes are linked to inflammation and
susceptibility to infection, their mechanistic contributions to immune outcomes remain ill …
susceptibility to infection, their mechanistic contributions to immune outcomes remain ill …
Cell death in photodynamic therapy: From oxidative stress to anti-tumor immunity
Photodynamic therapy is a promising approach for cancer treatment that relies on the
administration of a photosensitizer followed by tumor illumination. The generated oxidative …
administration of a photosensitizer followed by tumor illumination. The generated oxidative …
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
A Loboda, M Damulewicz, E Pyza, A Jozkowicz… - Cellular and molecular …, 2016 - Springer
The multifunctional regulator nuclear factor erythroid 2-related factor (Nrf2) is considered not
only as a cytoprotective factor regulating the expression of genes coding for anti-oxidant …
only as a cytoprotective factor regulating the expression of genes coding for anti-oxidant …
[HTML][HTML] Is melatonin the cornucopia of the 21st century?
N Ferlazzo, G Andolina, A Cannata, MG Costanzo… - Antioxidants, 2020 - mdpi.com
Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …
A pharmacological update of ellagic acid
JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018 - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …
present either in free form or as part of more complex molecules (ellagitannins), which can …
Modulation of oxidative stress as an anticancer strategy
The regulation of oxidative stress is an important factor in both tumour development and
responses to anticancer therapies. Many signalling pathways that are linked to …
responses to anticancer therapies. Many signalling pathways that are linked to …
Antioxidants and human diseases
P Rajendran, N Nandakumar, T Rengarajan… - Clinica chimica acta, 2014 - Elsevier
Oxidative stress plays a pivotal role in the development of human diseases. Reactive
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …
Mammalian heat shock response and mechanisms underlying its genome-wide transcriptional regulation
The heat shock response (HSR) is critical for survival of all organisms. However, its scope,
extent, and the molecular mechanism of regulation are poorly understood. Here we show …
extent, and the molecular mechanism of regulation are poorly understood. Here we show …