A fundamental goal in cancer research is to understand the mechanisms of cell
transformation. This is key to developing more efficient cancer detection methods and …

Aging is a physiological process mediated by numerous biological and genetic pathways,
which are directly linked to lifespan and are a driving force for all age-related diseases …

Epigenetic alternations concern heritable yet reversible changes in histone or DNA
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …

Today, bio-medical efforts are entering the subcellular level, which is witnessed with the fast-
developing fields of nanomedicine, nanodiagnostics and nanotherapy in conjunction with …

The past decade has seen the emergence of immunotherapy as a prime approach to cancer
treatment, revolutionizing the management of many types of cancer. Despite the promise of …

A biomarker is a physiological observable marker that acts as a stand-in and, in the best-
case scenario, forecasts a clinically significant outcome. Diagnostic biomarkers are more …

Efficient cancer immunotherapy depends on selective targeting of high bioactivity
therapeutic agents to the tumours. However, delivering exogenous medication might prove …

Histone posttranslational modifications represent a versatile set of epigenetic marks
involved not only in dynamic cellular processes, such as transcription and DNA repair, but …

Simple Summary Beyond mutations, epigenetic changes have been described as drivers for
cancer as well. While leaving the overall DNA structure intact, they can be responsible for …

The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …