Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …

Over the past several decades, the approach to the diagnosis and management of patients
with follicular cell‐derived thyroid cancer has evolved based on improved classification of …

Background Combined therapy with dabrafenib plus trametinib was approved in several
countries for treatment of BRAF V600E-mutant anaplastic thyroid cancer (ATC) based on an …

Importance Anaplastic thyroid carcinoma (ATC) historically has a 4-month median overall
survival (OS) from time of diagnosis, with disease-specific mortality approaching 100%. The …

Pediatric low-grade gliomas (pLGG) show heterogeneous responses to MAPK inhibitors
(MAPKi) in clinical trials. Thus, more complex stratification biomarkers are needed to identify …

Background: Sex dimorphism strongly impacts tumor biology, with most cancers having a
male predominance. Uniquely, thyroid cancer (TC) is the only nonreproductive cancer with …

Purpose: Fibroblast activation protein (FAP) is a promising target for tumor treatment. In this
study, we aimed to investigate the safety and efficacy of the albumin binder-conjugated FAP …

Most malignant thyroid tumours are initially treated with surgery or a combination of surgery
and radioactive iodine (RAI) therapy. However, in patients with metastatic disease, many …

The molecular characterization of poorly and anaplastic thyroid carcinomas has been
greatly improved in the last years following the advent of high throughput technologies …

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