The limited availability of transplantable organs hinders the success of patient treatment
through organ transplantation. In addition, there are challenges with immune rejection and …

Pain is the most frequent symptom of osteoarthritis (OA), occurring much more commonly
than stiffness or disability. Classically, OA-related pain has been considered to be a …

Osteoarthritis (OA) is a common degenerative joint disease worldwide and currently there is
no effective strategy to stop its progression. It is known that oxidative stress and inflammation …

The mechanism of the balance between subchondral angiogenesis and articular damage
within osteoarthritis (OA) progression remains a mystery. However, the lack of specific drugs …

Purpose The aim of this European Society of Sports Traumatology, Knee Surgery and
Arthroscopy (ESSKA) consensus is to provide recommendations based on evidence and …

Approaches to the design and construction of biomimetic scaffolds for osteochondral tissue,
show increasing advances. Considering the limitations of this tissue in terms of repair and …

Rheumatoid arthritis (RA), osteoarthritis (OA), and gout are the most prevalent degenerative
joint diseases (DJDs). The pathogenesis underlying joint disease in DJDs remains unclear …

The unprecedented rise in life expectancy observed in the last decades is leading to a
global increase in the ageing population, and age-associated diseases became an …

Background Short-stay joint replacement programmes are used in many countries but there
has been little scrutiny of safety outcomes in the literature. We aimed to systematically …

Purpose To characterize the safety, efficacy, and potential role of genicular artery
embolization (GAE) as a disease-modifying treatment for symptomatic knee osteoarthritis …