Clinical and biological aspects of disseminated tumor cells and dormancy in breast cancer

A Ring, M Spataro, A Wicki, N Aceto - Frontiers in Cell and …, 2022 - frontiersin.org
Progress in detection and treatment have drastically improved survival for early breast
cancer patients. However, distant recurrence causes high mortality and is typically …

Tumor-derived extracellular vesicle drug delivery system for chemo-photothermal-immune combination cancer treatment

Y Bi, J Chen, Q Li, Y Li, L Zhang, L Zhida, F Yuan… - Iscience, 2024 - cell.com
Tumor extracellular vesicles (EVs) demonstrate considerable promise for medication
delivery and tumor targeting owing to their natural long-term blood circulation and tissue …

Recent advances in lab-on-a-chip systems for breast cancer metastasis research

B Firatligil-Yildirir, O Yalcin-Ozuysal - Nanoscale Advances, 2023 - pubs.rsc.org
Breast cancer is the leading cause of cancer-related deaths in women. Multiple molecular
subtypes, heterogeneity, and their ability to metastasize from the primary site to distant …

Therapeutics targeting the metastatic breast cancer bone microenvironment

CL Ihle, SJ Wright-Hobart, P Owens - Pharmacology & Therapeutics, 2022 - Elsevier
Breast cancer (BC) patient prognosis has improved over the past 2 decades with a 99% 5-
year survival rate for localized BC, yet metastatic breast cancer (mBC) continues to cause …

Inflammation, nutrition, and clinical outcomes in breast cancer survivors: A narrative review

MK Pannu, C Constantinou - Current Nutrition Reports, 2023 - Springer
Abstract Purpose of Review Breast cancer (BC) is the leading cause of death among women
aged 44–55 years globally. Pro-inflammatory food can cause tissue-level inflammation …

Polyethyleneimine-based lipopolyplexes as carriers in anticancer gene therapies

J Jerzykiewicz, A Czogalla - Materials, 2021 - mdpi.com
Recent years have witnessed rapidly growing interest in application of gene therapies for
cancer treatment. However, this strategy requires nucleic acid carriers that are both effective …

High levels of unfolded protein response component CHAC1 associates with cancer progression signatures in malignant breast cancer tissues

V Mehta, P Suman, H Chander - Clinical and Translational Oncology, 2022 - Springer
Purpose The aberrant mRNA expression of a UPR component Cation transport regulator
homolog 1 (CHAC1) has been reported to be associated with poor survival in breast and …

“Cluster Bomb” Based Bismuth Nano‐in‐Micro Spheres Formed Dry Powder Inhalation for Thermo‐Radio Sensitization Effects of Lung Metastatic Breast Cancer

Q Wang, J Liu, D Chen, S Miao, J Wen… - Advanced …, 2023 - Wiley Online Library
Lung metastatic breast cancer (LMBC) is mainly diagnosed through CT imaging and
radiotherapy could be the most common method in the clinic to inhibit tumor proliferation …

Timing evolution of lobular breast cancer through phylogenetic analysis

D Fimereli, D Venet, M Rediti, B Boeckx, M Maetens… - …, 2022 - thelancet.com
Background Late distant recurrence is a challenge for the treatment of invasive lobular
carcinoma (ILC) of the breast. Despite in-depth characterisation of primary ILC, the …

ETV7 reduces inflammatory responses in breast cancer cells by repressing the TNFR1/NF-κB axis

EM Meškytė, L Pezzè, L Bartolomei, M Forcato… - Cell Death & …, 2023 - nature.com
The transcription factor ETV7 is an oncoprotein that is up-regulated in all breast cancer (BC)
types. We have recently demonstrated that ETV7 promoted breast cancer progression by …