Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

Colorectal cancer (CRC) ranks as the third most aggressive tumor globally, and it can be
categorized into two forms: colitis-mediated CRC and sporadic CRC. The therapeutic …

Because survival of patients with metastatic colorectal cancer remain poor, there is an
urgent need to identify potential novel druggable targets that are associated with colorectal …

Cancer is one of the greatest dangers to human wellbeing and survival. A key barrier to
effective cancer therapy is development of resistance to anti‑cancer medications. In cancer …

Colorectal cancer (CRC) is a serious global health concern, with a high incidence and
mortality rate. Although there have been advancements in the early detection and treatment …

Colorectal cancer (CRC), a tumor of the digestive system, is characterized by high
malignancy and poor prognosis. Currently, targeted therapy of CRC is far away from …

Thyroid hormone receptor-interacting protein 13 (TRIP13) is involved in cancer progression,
but its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. Thus, we assessed the …

Sulforaphane is one of the most characterized isothiocyanate compounds in cruciferous
vegetables and shows anticancer effects, especially antileukemia properties. However, the …

Infection with viruses, bacteria, and parasites are thought to be the underlying cause of
about 8–17% of the world's cancer burden, ie, approximately one in every five malignancies …