The recent advent of positron emission tomography (PET) scanners that can image the
entire human body opens up intriguing possibilities for cardiovascular research and future …

Murine models have been utilized with increasing frequency mainly due to availability of
genetically engineered models. With advancement in high spatial and temporal resolution …

PET is used in laboratory small-animal research to visualize and track certain molecular
processes associated with diseases such as cancer, heart disease, and neurologic …

The ability to trace or identify specific molecules within a specific anatomic location provides
insight into metabolic pathways, tissue components, and tracing of solute transport …

CD39 (ectonucleoside triphosphate diphosphohydrolase-1; ENTPD-1) rapidly hydrolyzes
ATP and ADP to AMP; AMP is hydrolyzed by ecto-5′-nucleotidase (CD73) to adenosine, an …

Background Cardiovascular disease (CVD) is associated with the apolipoprotein E (APOE)
gene and lipid metabolism. This study aimed to develop an imaging-based pipeline to …

Traumatic brain injury (TBI) results in systemic inflammatory responses that affect the lung.
This is especially critical in the setting of lung transplantation, where more than half of donor …

Exercise-induced cardiac hypertrophy has been recently identified to be regulated in a sex-
specific manner. In parallel, women exhibit enhanced exercise-mediated lipolysis compared …

Existing preclinical methods for acquiring dissemination kinetics of rare circulating tumor
cells (CTCs) en route to forming metastases have not been capable of providing a direct …

This methodical work describes the measurement and calculation of pulmonary blood
volume in mice based on two imaging techniques namely by using magnetic particle …