Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …

Poor wound healing after diabetes mellitus remains a challenging problem, and its
pathophysiological mechanisms have not yet been fully elucidated. Persistent bleeding …

The blood vessel system is essential for skin homeostasis and regeneration. While the
heterogeneity of vascular endothelial cells has been emergingly revealed, whether a …

Background Wound healing is a complex and dynamic process that involves a series of
cellular and molecular events. Mesenchymal stem cells (MSCs) and their exosomes (MSC …

Background Macro minerals, also known as macro elements, are minerals that are required
in large amounts in the human body. Macro minerals are part of the biological structure of …

Exercise, psychosocial stress, and drugs such as adrenergic agonists and antagonists
increase the concentrations of catecholamines and/or alter adrenergic signaling …

Normal placental development and proper angiogenesis are essential for fetal growth
during pregnancy. Angiogenesis involves the regulatory action of many angiogenic factors …

In this review, we discuss sympathetic regulation in normal and diabetic wound healing.
Experimental denervation studies have confirmed that sympathetic nerve endings in skin …

Tumor recurrence and chronic bacterial infection constitute two major criteria in postsurgical
intervention for malignant melanoma. One plausible strategy is the equipment of …

Mast cells are evolutionarily old cells and the principal effectors in allergic responses and
inflammation. They are seeded from the yolk sac during embryogenesis or are derived from …