Diffuse myocardial fibrosis: mechanisms, diagnosis and therapeutic approaches
B López, S Ravassa, MU Moreno, GS José… - Nature Reviews …, 2021 - nature.com
Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …
Exercise‐based cardiac rehabilitation for adults with heart failure
Background Chronic heart failure (HF) is a growing global health challenge. People with HF
experience substantial burden that includes low exercise tolerance, poor health‐related …
experience substantial burden that includes low exercise tolerance, poor health‐related …
Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic …
BK Kim, SJ Hong, YJ Lee, SJ Hong, KH Yun, BK Hong… - The Lancet, 2022 - thelancet.com
Background Drug combinations rather than increasing doses of one drug can achieve
greater efficacy and lower risks. Thus, as an alternative to high-intensity statin monotherapy …
greater efficacy and lower risks. Thus, as an alternative to high-intensity statin monotherapy …
Health-related quality of life and mortality in heart failure: the global congestive heart failure study of 23 000 patients from 40 countries
I Johansson, P Joseph, K Balasubramanian… - Circulation, 2021 - Am Heart Assoc
Background: Poor health-related quality of life (HRQL) is common in heart failure (HF), but
there are few data on HRQL in HF and the association between HRQL and mortality outside …
there are few data on HRQL in HF and the association between HRQL and mortality outside …
The COMET handbook: version 1.0
PR Williamson, DG Altman, H Bagley, KL Barnes… - Trials, 2017 - Springer
The selection of appropriate outcomes is crucial when designing clinical trials in order to
compare the effects of different interventions directly. For the findings to influence policy and …
compare the effects of different interventions directly. For the findings to influence policy and …
Anti-inflammatory therapy with canakinumab for the prevention of hospitalization for heart failure
Background: Subclinical inflammation is associated with an increased risk of heart failure
and with adverse prognosis in patients with established heart failure. Yet, treatments …
and with adverse prognosis in patients with established heart failure. Yet, treatments …
Role of biomarkers for the prevention, assessment, and management of heart failure: a scientific statement from the American Heart Association
SL Chow, AS Maisel, I Anand, B Bozkurt, RA De Boer… - Circulation, 2017 - Am Heart Assoc
Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …
prognostic tool for the diagnosis and management of heart failure (HF). More recent …
2014 ACC/AHA key data elements and definitions for cardiovascular endpoint events in clinical trials: a report of the American College of Cardiology/American Heart …
KA Hicks, JE Tcheng, B Bozkurt, BR Chaitman… - Circulation, 2015 - Am Heart Assoc
This publication, commissioned by the ACC/AHA, is the product of a novel collaboration
between the ACC and AHA, the US Food and Drug Administration (FDA), and the …
between the ACC and AHA, the US Food and Drug Administration (FDA), and the …
Levosimendan efficacy and safety: 20 years of SIMDAX in clinical use
Levosimendan was first approved for clinical use in 2000, when authorization was granted
by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely …
by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely …
Core outcome Set-STAndardised protocol items: the COS-STAP statement
Background Several hundred core outcome set (COS) projects have been systematically
identified to date which, if adopted, ensure that researchers measure and report those …
identified to date which, if adopted, ensure that researchers measure and report those …