The term 'stress'–coined in 1936–has many definitions, but until now has lacked a
theoretical foundation. Here we present an information-theoretic approach–based on the …

Serhan and colleagues introduced the term" Resoleomics" in 1996 as the process of
inflammation resolution. The major discovery of Serhan's work is that onset to conclusion of …

High cardiovascular mortality is well documented in lean phenotypes exhibiting visceral fat
accumulation. In contrast, corpulent phenotypes with predominantly subcutaneous fat …

Insulin resistance (IR) is a general phenomenon of many physiological states, disease
states, and diseases. IR has been described in diabetes mellitus, obesity, infection, sepsis …

Obesity and type 2 diabetes have become the major health problems in many industrialized
countries. Here, I present the unconventional concept that a healthy organism maintains its …

Despite decades of research, the pathophysiology and aetiology of schizophrenia remains
incompletely understood. The disorder is frequently accompanied by metabolic symptoms …

During acute mental stress, the energy supply to the human brain increases by 12%. To
determine how the brain controls this demand for energy, 40 healthy young men participated …

During the course of evolution, up until the agricultural revolution, environmental fluctuations
forced the human species to develop a flexible metabolism in order to adapt its energy …

The brain occupies a special hierarchical position in human energy metabolism. If cerebral
homeostasis is threatened, the brain behaves in a “selfish” manner by competing for energy …

People who habituate to stress show a repetition-induced response attenuation—
neuroendocrine, cardiovascular, neuroenergetic, and emotional—when exposed to a …