The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Eukaryotic cells can undergo different forms of programmed cell death, many of which
culminate in plasma membrane rupture as the defining terminal event,,,,,–. Plasma …

Biosynthesis of many important polysaccharides (including peptidoglycan,
lipopolysaccharide, and N-linked glycans) necessitates the transport of lipid-linked …

The host proteins SERINC3 and SERINC5 are HIV-1 restriction factors that reduce infectivity
when incorporated into the viral envelope. The HIV-1 accessory protein Nef abrogates …

MFSD2A is a sodium-dependent lysophosphatidylcholine symporter that is responsible for
the uptake of docosahexaenoic acid into the brain,, which is crucial for the development and …

Nucleic acid–sensing Toll-like receptors (TLRs) play a pivotal role in innate immunity by
recognizing foreign DNA and RNA. Compartmentalization of these TLRs in the endosome …

Major Facilitator Superfamily Domain containing 2a (Mfsd2a) is a sodium-dependent
lysophosphatidylcholine (LPC) transporter expressed at the blood–brain barrier that …

Brain development and function require uptake of essential omega-3 fatty acids in the form
of lysophosphatidylcholine via major-facilitator superfamily transporter MFSD2A, a potential …

The movement of lipids within and between membranes in bacteria is essential for building
and maintaining the bacterial cell envelope. Moving lipids to their final destination is often …

Dear Editor, As one of the critical sphingolipid metabolites in eukaryotes, sphingosine-1-
phosphate (S1P) acts as a bioactive lipid mediator in the immune and vascular systems …