[HTML][HTML] Neurotrophic factor BDNF, physiological functions and therapeutic potential in depression, neurodegeneration and brain cancer

L Colucci-D'Amato, L Speranza, F Volpicelli - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

[HTML][HTML] BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity

P Kowiański, G Lietzau, E Czuba, M Waśkow… - Cellular and molecular …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …

[HTML][HTML] Recent advances on the role of brain-derived neurotrophic factor (BDNF) in neurodegenerative diseases

KF Azman, R Zakaria - International journal of molecular sciences, 2022 - mdpi.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

[HTML][HTML] The role of brain derived neurotrophic factor in central nervous system

Y Li, F Li, D Qin, H Chen, J Wang, J Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …

Chronic stress weakens connectivity in the prefrontal cortex: architectural and molecular changes

E Woo, LH Sansing, AFT Arnsten, D Datta - Chronic Stress, 2021 - journals.sagepub.com
Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the
prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of …

The emerging role of the BDNF-TrkB signaling pathway in the modulation of pain perception

N Cappoli, E Tabolacci, P Aceto, CD Russo - Journal of neuroimmunology, 2020 - Elsevier
The brain derived neurotrophic factor (BDNF) is a crucial neuromodulator in pain
transmission both in peripheral and central nervous system (CNS). Despite evidence of a …

[HTML][HTML] Mechanisms that modulate and diversify BDNF functions: implications for hippocampal synaptic plasticity

AP De Vincenti, AS Ríos, G Paratcha… - Frontiers in cellular …, 2019 - frontiersin.org
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has pleiotropic effects on
neuronal morphology and synaptic plasticity that underlie hippocampal circuit development …

Roles of myokines in exercise-induced improvement of neuropsychiatric function

S Kim, JY Choi, S Moon, DH Park, HB Kwak… - … -European Journal of …, 2019 - Springer
Exercise is a well-known non-pharmacological intervention to improve brain functions,
including cognition, memory, and motor coordination. Contraction of skeletal muscles during …

[HTML][HTML] The role of altered BDNF/TrkB signaling in amyotrophic lateral sclerosis

J Pradhan, PG Noakes, MC Bellingham - Frontiers in cellular …, 2019 - frontiersin.org
Brain derived neurotrophic factor (BDNF) is well recognized for its neuroprotective functions,
via activation of its high affinity receptor, tropomysin related kinase B (TrkB). In addition …

Peripheral brain-derived neurotrophic factor (BDNF) in insomnia: A systematic review and meta-analysis

A Ballesio, A Zagaria, DG Curti, R Moran… - Sleep medicine …, 2023 - Elsevier
The brain-derived neurotrophic factor (BDNF) is associated with emotional and cognitive
functioning, and it is considered a transdiagnostic biomarker for mental disorders. Literature …