[HTML][HTML] Oral squamous cell carcinoma: metastasis, potentially associated malignant disorders, etiology and recent advancements in diagnosis

A Bugshan, I Farooq - F1000Research, 2020 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC) is a commonly occurring head and neck cancer. It
has a high prevalence in certain parts of the world, and is associated with a high mortality …

Tumor-derived exosomes in the regulation of macrophage polarization

MS Baig, A Roy, S Rajpoot, D Liu, R Savai… - Inflammation …, 2020 - Springer
Background This review focuses on exosomes derived from various cancer cells. The review
discusses the possibility of differentiating macrophages in alternatively activated anti …

Exosomes derived from hypoxic oral squamous cell carcinoma cells deliver miR-21 to normoxic cells to elicit a prometastatic phenotype

L Li, C Li, S Wang, Z Wang, J Jiang, W Wang, X Li… - Cancer research, 2016 - AACR
Hypoxia is a common feature of solid tumors and is associated with aggressiveness and
poor patient outcomes. Exosomes, initially considered to be cellular “garbage dumpsters,” …

Epidemiologic trends in head and neck cancer and aids in diagnosis

N Vigneswaran, MD Williams - Oral and …, 2014 - oralmaxsurgery.theclinics.com
Head and neck cancers represent the sixth most common cancer worldwide, with
approximately 630,000 new patients diagnosed annually resulting in more than 350,000 …

[HTML][HTML] Salivary exosomes: emerging roles in systemic disease

Y Han, L Jia, Y Zheng, W Li - International journal of biological …, 2018 - ncbi.nlm.nih.gov
Saliva, which contains biological information, is considered a valuable diagnostic tool for
local and systemic diseases and conditions because, similar to blood, it contains important …

Prognostic evaluation of oral tongue cancer: means, markers and perspectives (II)

IO Bello, Y Soini, T Salo - Oral oncology, 2010 - Elsevier
Squamous cell carcinoma of the oral (mobile) tongue (OTSCC) is increasingly regarded as a
biologically different entity compared to cancer affecting other oral sites. It is more …

HSP‐enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells

K Ono, T Eguchi, C Sogawa… - Journal of cellular …, 2018 - Wiley Online Library
Cancer cells often secrete extracellular vesicles (EVs) that carry heat shock proteins (HSPs)
with roles in tumor progression. Oral squamous cell carcinoma (OSCC) belongs to head and …

Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells

S Krishnamurthy, Z Dong, D Vodopyanov, A Imai… - Cancer research, 2010 - AACR
Recent studies have demonstrated that cancer stem cells play an important role in the
pathobiology of head and neck squamous cell carcinomas (HNSCC). However, little is …

Cancer stem cells in oral cavity squamous cell carcinoma: a review

R Baillie, ST Tan, T Itinteang - Frontiers in Oncology, 2017 - frontiersin.org
Cancer stem cells (CSCs) have been identified in oral cavity squamous cell carcinoma
(OCSCC). CSCs possess the ability for perpetual self-renewal and proliferation, producing …

Cisplatin induces Bmi-1 and enhances the stem cell fraction in head and neck cancer

C Nör, Z Zhang, KA Warner, L Bernardi, F Visioli… - Neoplasia, 2014 - Elsevier
Recent evidence has unveiled a subpopulation of highly tumorigenic, multipotent cells
capable of self-renewal in head and neck squamous cell carcinomas (HNSCCs). These …