Organ development and homeostasis involve dynamic interactions between individual cells
that collectively regulate tissue architecture and function. To ensure the highest tissue …

The process of embryonic development involves remarkable cellular plasticity, which
governs the coordination between cells necessary to build an organism. One role of this …

Cell competition acts as a quality-control mechanism that eliminates cells less fit than their
neighbors to optimize organ development. Whether and how competitive interactions occur …

Normal epithelial cells exert their competitive advantage over RasV12-transformed cells and
eliminate them into the apical lumen via cell competition. However, the internal or external …

Epithelial cell death is highly prevalent during development and tissue homeostasis. While
we have a rather good understanding of the molecular regulators of programmed cell death …

Cell-cell interactions are central to development, but exploring how a change in any given
cell relates to changes in the neighbour of that cell can be technically challenging. Here, we …

Experimental Embryology is often referred to as a classical approach of developmental
biology that has been to some extent replaced by the introduction of molecular biology and …

Non-human primates (NHPs) are increasingly used in preclinical trials to test the safety and
efficacy of biotechnology therapies. Nonetheless, given the ethical issues and costs …

Effective multicellularity requires both cooperation and competition between constituent
cells. Cooperation involves sacrificing individual fitness in favour of that of the community …

The human embryo selection arena is associated with transposable element activity | PLOS
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