Polyunsaturated fatty acids (PUFAs), particularly the ω-3 PUFAs and COXIBs have been
associated with decreased inflammation and the prevention of tumorigenesis. ω-3 PUFAs …

Sulfur dioxide (SO2) is a common air pollutant, and inhaled SO2 in airway epithelium easily
forms its soluble derivatives in vivo (bisulfite and sulfite), which are toxic to the respiratory …

Dimethylcelecoxib (DMC), a derivative of celecoxib, has been developed to distinguish
between the COX-dependent and COX-independent anti-carcinogenic effects of celecoxib …

Human pancreatic carcinoma is known for its aggressiveness, low survival rate, and
attractive target for anticancer evaluation. To target pancreatic cancer, new anticancer …

COX-2 induces the proliferation and invasion of oral squamous cell carcinoma. In the
present study, the role of the COX-2 gene in the tongue cancer cell proliferation and …

Dexamethasone, a common medication used in the treatment regimen of glioblastoma, has
broad inhibitory effects on the immune responses. Here, in an in vitro study, we examined …

Background: The prognostic and predictive role of cyclo-oxygenase-2 (COX2) in breast
cancer is still debated, and in particular, its role as a target of COX2 inhibitor (celecoxib) in …

Photodynamic therapy (PDT) effectiveness can be improved by employing combined
modality approaches involving pharmaceuticals targeting the tumor microenvironment …

Abstract We prepared 11 C-labeled5-(4-chlorophenyl)-l-(4-methoxyphenyl)-3-
(trifluoromethyl)-lH-pyrazole ([11 C] 1) and 4-[5-(4-methoxyphenyl)-3-trifluoromethyl-lH …

Objective: Spirodela polyrhiza (L.) Sch. is widely used in Korean traditional medicine. No
previous work has investigated in detail the anti-inflammatory activities of S. polyrhiza or …