Heteromeric T1R2/T1R3 taste receptors

M Zoller, X Li, L Staszewski, S O'connell… - US Patent …, 2012 - Google Patents
G01N33/5008—Chemical analysis of biological material, eg blood, urine; Testing involving
biospecific ligand binding methods; Immunological testing involving human or animal cells …

Methods of inhibiting T1R1/T1R3 heteromeric umami taste receptors

M Zoller, X Li, L Staszewski, S O'connell… - US Patent …, 2012 - Google Patents
Oct. 31, 2007, now abandoned, which is a division of 7,763,431 B1 7/2010 Zoller et al.
application No. 10/179,373, filed on Jun. 26, 2002, 7,772,385 B2 8/2010 Adler et al. now …

Binding and functional assays that use the T1R3 receptor to screen for taste modulatory compounds

JE Adler, S Zozulya, X Li, S O'connell… - US Patent …, 2014 - Google Patents
Newly identified mammalian taste-cell-specific G protein coupled receptors, and the genes
and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled …

Human T1R2 taste receptor nucleic acids and cells containing these nucleic acids

JE Adler, X Li, L Staszewski, S O'connell… - US Patent …, 2012 - Google Patents
Newly identified mammalian taste-cell-specific G protein coupled receptors, and the genes
and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled …

T1R taste receptors and genes encoding same

JE Adler, S Zozulya, X Li, S O'connell… - US Patent …, 2012 - Google Patents
Newly identified mammalian taste-cell-specific G protein coupled receptors, and the genes
and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled …

Methods of indentifying sweet taste modulators

JE Adler, X Li, L Staszewski, H Xu… - US Patent 8,119,359, 2012 - Google Patents
(*) Notice: Subject to any disclaimer, the term of this 7,534,577 B2 5/2009 NE I. patent is
extended or adjusted under 35 7,588,900 B2 9/2009 Zuker et al. USC 154 (b) by 0 days …

T1R3 nucleic acid fragments for use thereof as probes and for generating T1R specific antibodies

JE Adler, S Zozulya, X Li, S O'connell… - US Patent …, 2012 - Google Patents
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes
and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled …

Assays that detect T1R expressing cells

JE Adler, S Zozulya, X Li, S O'connell… - US Patent …, 2012 - Google Patents
(60) Provisional application No. 60/187.546, filed on Mar. 7, 2000, provisional application
No. 60/195.536, filed on Apr. 7, 2000, provisional application No. 60/209,840, filed on Jun. 6 …

Methods of screening heteromeric T1R2/T1R3 receptors which modulate sweet taste signaling

M Zoller, X Li, L Staszewski, S O'connell… - US Patent …, 2012 - Google Patents
Related US Application Data(74) Attorney, Agent, or Firm—Hunton & Williams LLP (60)
Division of application No. 12/270,838, filed on Nov. 13, 2008, now Pat. No. 7,910,322 …

Methods of detecting T1R2-and T1R3-expressing cells potentially sensitive to sweet tastants

M Zoller, X Li, L Staszewski, S O'connell… - US Patent …, 2012 - Google Patents
(60) Division of application No. 12/270.824, filed on Nov. US Appl. No. 1 1/939,415,
unpublished, Zoller et al. 13, 2008, now Pat. No. 7,906,328, which is a US Appl. No. 1 …