Ferroptosis: the potential value target in atherosclerosis
S Ouyang, J You, C Zhi, P Li, X Lin, X Tan, W Ma… - Cell Death & …, 2021 - nature.com
In advanced atherosclerosis (AS), defective function-induced cell death leads to the
formation of the characteristic necrotic core and vulnerable plaque. The forms and …
formation of the characteristic necrotic core and vulnerable plaque. The forms and …
Pathological roles of iron in cardiovascular disease
M Kobayashi, T Suhara, Y Baba… - Current drug …, 2018 - ingentaconnect.com
Iron is an essential mineral required for a variety of vital biological functions. Despite being
vital for life, iron also has potentially toxic aspects. Iron has been investigated as a risk factor …
vital for life, iron also has potentially toxic aspects. Iron has been investigated as a risk factor …
DiDang decoction improves mitochondrial function and lipid metabolism via the HIF-1 signaling pathway to treat atherosclerosis and hyperlipidemia
X Wu, J Pan, JJJ Yu, J Kang, S Hou, M Cheng… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance DiDang Decoction (DDD) is a traditional classical
prescription that has been used to treat atherosclerosis (AS) and hyperlipidemia (HLP) in …
prescription that has been used to treat atherosclerosis (AS) and hyperlipidemia (HLP) in …
Iron overload, oxidative stress and vascular dysfunction: Evidences from clinical studies and animal models
L Dos Santos, SR Bertoli, RA Ávila… - Biochimica et Biophysica …, 2022 - Elsevier
Although iron is a metal involved in many vital processes due to its redox capacity, body iron
overloads lead to tissue damage, including the cardiovascular system. While …
overloads lead to tissue damage, including the cardiovascular system. While …
Non-transferrin-bound iron in the spotlight: novel mechanistic insights into the vasculotoxic and atherosclerotic effect of iron
F Vinchi - Antioxidants & Redox Signaling, 2021 - liebertpub.com
Significance: While atherosclerosis is an almost inevitable consequence of aging, food
preferences, lack of exercise, and other aspects of the lifestyle in many countries, the …
preferences, lack of exercise, and other aspects of the lifestyle in many countries, the …
Association of serum ferritin levels with metabolic syndrome and insulin resistance in a Chinese population
L Chen, Y Li, F Zhang, S Zhang, X Zhou, L Ji - Journal of Diabetes and its …, 2017 - Elsevier
Aims Increased iron is associated with type 2 diabetes, dyslipidemia, and high blood
pressure. Therefore, serum ferritin may be a suitable biomarker to detect metabolic …
pressure. Therefore, serum ferritin may be a suitable biomarker to detect metabolic …
The emerging role of IL-1 inhibition in patients affected by rheumatoid arthritis and diabetes
P Ruscitti, P Cipriani, V Liakouli… - Reviews on Recent …, 2018 - ingentaconnect.com
Background: Although in the past, prevention of the joint destruction and disability was
strongly emphasised in Rheumatoid Arthritis (RA), at present, a growing body of evidence is …
strongly emphasised in Rheumatoid Arthritis (RA), at present, a growing body of evidence is …
Extracellular vesicles from thalassemia patients carry iron-containing ferritin and hemichrome that promote cardiac cell proliferation
A Atipimonpat, P Siwaponanan, A Khuhapinant… - Annals of …, 2021 - Springer
Extracellular vesicles (EVs) are bioactive, submicron-sized membrane vesicles released
from all cell types upon activation or apoptosis. EVs including microparticles (MPs) and …
from all cell types upon activation or apoptosis. EVs including microparticles (MPs) and …
Endocan—the new endothelial activation marker independently associated with soluble endothelial adhesion molecules in uraemic patients with cardiovascular …
K Pawlak, M Mysliwiec, D Pawlak - Clinical Biochemistry, 2015 - Elsevier
Objectives Endocan is a new marker of endothelial cell activation that mediates adhesion of
leukocytes into endothelium. Soluble intercellular (sICAM-1) and vascular cellular (sVCAM …
leukocytes into endothelium. Soluble intercellular (sICAM-1) and vascular cellular (sVCAM …
Cyanotic congenital heart disease and atherosclerosis
JB Tarp, AS Jensen, T Engstrøm, NH Holstein-Rathlou… - Heart, 2017 - heart.bmj.com
Improved treatment options in paediatric cardiology and congenital heart surgery have
resulted in an ageing population of patients with cyanotic congenital heart disease (CCHD) …
resulted in an ageing population of patients with cyanotic congenital heart disease (CCHD) …