Human endogenous retroviruses (HERVs) represent∼ 8% of human genome, deriving from
exogenous retroviral infections of germ line cells occurred millions of years ago and being …

Transposable elements (TEs), also known as mobile elements (MEs), are interspersed
repeats that constitute a major fraction of the genomes of higher organisms. As one of their …

Endogenous retroviruses (ERVs) have been reported to participate in pre-implantation
development of mammalian embryos. In early human embryogenesis, different ERV sub …

There remains much that we do not understand about the earliest stages of human
development. On a gross level, there is evidence for apoptosis, but the nature of the affected …

Transposable elements are the largest individual constituent of mammalian genomes.
These elements are highly diverse, a consequence of the multiplicity of genomic habitats …

Bi-directional transcription of Human Endogenous Retroviruses (hERVs) is a common
feature of autoimmunity, neurodegeneration and cancer. Higher rates of cancer incidence …

Novel genes are essential for evolutionary innovations and differ substantially even between
closely related species. Recently, multiple studies across many taxa showed that some …

Abstract Background Human endogenous retroviruses (HERVs) occupy a substantial
fraction of the genome and impact cellular function with both beneficial and deleterious …

Germline development varies significantly across metazoans. However, mammalian
primordial germ cell (PGC) development has key conserved landmarks, including a critical …

Endogenous retroviral sequences provide a molecular fossil record of ancient infections
whose analysis might illuminate mechanisms of viral extinction. A close relative of …