Human cytochrome P450 enzymes (CYPs) play a critical role in various biological
processes and human diseases. CYP1 family members, including CYP1A1, CYP1A2, and …

Coffee is a beverage consumed globally. Although few studies have indicated adverse
effects, it is typically a beneficial health-promoting agent in a range of diseases, including …

This study investigates the potential correlation between urinary caffeine levels and the
occurrence of stroke, a serious cerebrovascular disease that can lead to disability or death …

Background Hypertension increases the likelihood of cardiovascular diseases (CVDs).
Cytochrome P450 1A2 (CYP1A2) single nucleotide polymorphism (SNP) is related to …

Objective Genetic variation in the methylenetetrahydrofolate reductase (MTHFR) gene may
contribute to the development of cerebral infarction (CI); however, results have been …

Aim: CYP1A1 is a metabolizing enzyme and key polymorphisms in its gene may contribute
to the risk of ischemic stroke. This study aimed to investigate the association of the …

Background Cerebral stroke (stroke) is an acute cerebrovascular disease with high
incidence and mortality. This study aimed to explore the association between single …

Background Stroke has a high disability rate, and 30% of stroke cases have an unknown
cause. Accurate diagnosis and treatment of stroke requires consideration of several rare …

Background Pulmonary small airway epithelia are the primary site of cellular and
histological alterations in chronic obstructive pulmonary disease (COPD), while the potential …