The persistent triploid endosperms of cereal crops are the most important source of human
food and animal feed. The development of cereal endosperms progresses through …

The two mannose 6-phosphate (M6P) receptors were identified because of their ability to
bind M6P-containing soluble acid hydrolases in the Golgi and transport them to the …

Imprinted genes in mammals are expressed from only one of the parental chromosomes,
and are crucial for placental development and fetal growth,,,. The insulin-like growth factor II …

I. Overview T HE general characterization of the growth hormone/insulin-like growth factor-I
(GH/IGF-I) system has been established for a considerable length of time, and we will not …

The insulin-like growth factor (IGF) signaling pathway consists of multiple IGF ligands, IGF
receptors, and IGF-binding proteins (IGFBPs). Studies in a variety of animal and cellular …

Genome-wide scans for recent positive selection in humans have yielded insight into the
mechanisms underlying the extensive phenotypic diversity in our species, but have focused …

The environment in which the fetus develops is critical for its survival and long-term health.
The regulation of normal human fetal growth involves many multidirectional interactions …

Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle
performance, maintaining metabolic function and supporting longevity and healthspan …

It has been a controversial issue as to how many DNA cytosine methyltransferase
mammalian cells have and whether de novo methylation and maintenance methylation …

Cardiac myocytes rapidly proliferate during fetal life but exit the cell cycle soon after birth in
mammals. Although the extent to which adult cardiac myocytes are capable of cell cycle …