[HTML][HTML] MAPK/ERK signaling pathway in hepatocellular carcinoma

H Moon, SW Ro - Cancers, 2021 - mdpi.com
Simple Summary The mitogen-activated protein kinase/extracellular signal-regulated kinase
(MAPK/ERK) signaling pathway is frequently activated in liver cancer, which is one of the …

Immunotherapy for hepatocellular carcinoma

Y Zongyi, L Xiaowu - Cancer letters, 2020 - Elsevier
abstract Despite significant research efforts, only a few treatment approaches have been
developed for hepatocellular carcinoma (HCC). In recent years, immune checkpoint …

[HTML][HTML] Etiology of hepatocellular carcinoma: special focus on fatty liver disease

D Suresh, AN Srinivas, DP Kumar - Frontiers in Oncology, 2020 - frontiersin.org
Hepatocellular Carcinoma (HCC) is a highly aggressive cancer with mortality running
parallel to its incidence and has limited therapeutic options. Chronic liver inflammation and …

[HTML][HTML] Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

[HTML][HTML] Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies

J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

Therapeutic options in hepatocellular carcinoma: a comprehensive review

D Suresh, AN Srinivas, A Prashant… - Clinical and …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a chronic liver disease that is highly fatal if not detected
and treated early. The incidence and death rate of HCC have been increasing in recent …

[HTML][HTML] Molecular mechanisms behind safranal's toxicity to HepG2 cells from dual omics

DR Nelson, AA Hrout, AS Alzahmi, A Chaiboonchoe… - Antioxidants, 2022 - mdpi.com
The spice saffron (Crocus sativus) has anticancer activity in several human tissues, but the
molecular mechanisms underlying its potential therapeutic effects are poorly understood …

[HTML][HTML] Circ_0001955 facilitates hepatocellular carcinoma (HCC) tumorigenesis by sponging miR-516a-5p to release TRAF6 and MAPK11

Z Yao, R Xu, L Yuan, M Xu, H Zhuang, Y Li… - Cell death & …, 2019 - nature.com
Circular RNAs (circRNAs) have been increasingly demonstrated to function as novel
promising therapeutic RNA molecules for diverse human diseases, including cancer …

[HTML][HTML] Multikinase inhibitor treatment in thyroid cancer

OV Ancker, M Krüger, M Wehland, M Infanger… - International journal of …, 2019 - mdpi.com
Thyroid cancer is the most common endocrine malignancy. Most thyroid cancer types
respond well to conventional treatment consisting of surgery and radioactive iodine (RAI) …

[HTML][HTML] The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma

Z Zhang, X Tan, J Luo, H Yao, Z Si, JS Tong - Cell death & disease, 2020 - nature.com
HCC (hepatocellular carcinoma) is a major health threat for the Chinese population and has
poor prognosis because of strong resistance to chemotherapy in patients. For instance, a …