The solid dispersion has become an established solubilization technology for poorly water
soluble drugs. Since a solid dispersion is basically a drug–polymer two-component system …

Breast cancer (BC) is mostly observed in women and is responsible for huge mortality in
women subjects globally. Due to the continued development of drug resistance and other …

Solid dispersions are one of the most promising strategies to improve the oral bioavailability
of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and …

The liquid antisolvent (LAS) precipitation process for production of ultra-fine particles has
been widely researched for a last few decades. In LAS process, precipitation of solute is …

Estimation of drug–excipient interactions is a crucial step in preformulation studies of drug
development to achieve consistent stability, bioavailability and manufacturability of solid …

Chitosan (CS) nanoparticles of dorzolamide hydrochloride (Dorzo) and pramipexole
hydrochloride (Prami) were prepared by the ionic gelation method and their in vitro …

Amorphous solid dispersions (ASDs) are single-phase amorphous systems, where drug
molecules are molecularly dispersed (dissolved) in a polymer matrix. The molecular …

Introduction: In recent years, the number of active pharmaceutical ingredients with high
therapeutic impact, but very low water solubility, has increased significantly. Thus, a great …

In the present study the release mechanism of the sparingly water-soluble drug felodipine
(FELO) from particulate solid dispersions in PVP or PEG was investigated. FT-IR data …

Breast cancer is the most common malignancy worldwide, especially among women, with
substantial after-treatment effects. The survival rates of breast cancer have decreased over …